Early childhood growth retardation persists in developing countries despite decades of nutritional interventions. Adequate food is necessary, but not sufficient, to ensure normal growth where there is ubiquitous exposure to infection. Pathways associated with infection, small intestinal mucosal damage and chronic immunostimulation remain largely undemonstrated in countries other than The Gambia...

nonspecific activity-related arm pain is characterized by an absence of objective physical findings and symptoms that do not correspond with objective pathophysiology. arm pain without strict diagnosis is often related to activity, work-related activity in particular, and is often seen in patients with physically demanding work. psychological factors such as catastrophic thinking, symptoms of d...

The post-human genomic era has led to the development of therapies, which specifically target molecular pathways responsible for diseases. The original concept of antisense therapy was to simply turn off gene's activity by a short synthetic DNA sequence, having sequence complementary to mRNA and thus block the production of undesirable protein. However, during the last two decades this concept ...

Either of two immunostimulating factors (lpr, lipopolysaccharide) enhanced the pathogenic autoimmune responses of MRL/n mice, but the serologic and immunopathologic characteristics differed. In contrast, either factor acting alone, caused minimal immunopathology in normal mice, despite autoantibody induction. Combined immunostimulation, however, caused fatal glomerulonephritis in normal-backgro...