transforming growth factor-beta (tgf-β) is one of the most important cytokines implicated in growth, differentiation, repair and also the pathogenesis of the lung fibrosis by its stimulatory effect on extracellular matrix deposition. pulmonary epithelial cells are considered as a source of tgf-β in lung. substance p (sp), as a neuroimmunomodulator has elevated levels in inflamed airways and alt...

dr.mirsadraei and colleagues performed an interesting study about the lung hrct findings in chemical warfare patients who suffering from long-term pulmonary complications. they found that air trapping and mosaic attenuation were the most common lung hrct findings. also they divided patients in different clinical entities according to the lung hrct findings (bronchiolitis oblitrans, pulmonary fi...

Failure of development of the primitive lung bud leads to an extremely rare congenital anomaly with a prevalence of 34 per 10 lac live births termed pulmonary aplasia. In half of such cases, associated congenital malformations of the cardiovascular, skeletal, gastrointestinal, or genitourinary systems are present. The Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome is defined as the congenital a...

The aim of present study was to investigate the potential antioxidant and lung protective activities of Sambucus ebulus (SE) against toxicity induced by gamma irradiation. Hydroalcoholic extract of SE (20, 50 and 100 mg/kg) was studied for its lung protective activity. Phenol and flavonoid contents of SE were determined. Male C57 mice were divided into ten groups with five mice per group. Only ...

the aim of present study was to investigate the potential antioxidant and lung protective activities of sambucus ebulus (se) against toxicity induced by gamma irradiation. hydro alcoholic extract of se (20, 50 and 100 mg/kg ) was studied for its lung protective activity. . phenol and flavonoid contents of se were determined. male c57 mice were divided into 10 groups with five mice per group. on...