نتایج جستجو برای: nuclear factor kappa

تعداد نتایج: 1054869  

2012
Yongjun Jiang Juehua Zhu Li Wu Gelin Xu Jianwu Dai Xinfeng Liu

BACKGROUND Tetracycline exerts neuroprotection via suppressing the local inflammation induced by cerebral ischemia. However, the underlying mechanism is not completely clear. METHODOLOGY/PRINCIPAL FINDINGS The mRNA and protein expressions of tumor necrosis factor α and interleukin 6 and the number of activated microglia were measured to detect the inflammatory process in the ischemic hemisphe...

Journal: :The Journal of biological chemistry 2001
C Kanamaru H Yasuda M Takeda N Ueda J Suzuki T Tsuchida H Mashima H Ohnishi T Fujita

Activin A induces growth arrest of rat hepatocytes in vitro and in vivo. The alpha(1)-adrenergic agonist, norepinephrine (NE), enhances epidermal growth factor-stimulated DNA synthesis and inhibits activin A-induced growth inhibition, but the mechanisms of these actions are unclear. Smad proteins have recently been identified as intracellular signaling mediators of transforming growth factor-be...

Journal: :The Journal of Experimental Medicine 1994
M A Read M Z Whitley A J Williams T Collins

Structural analysis of the promoters of several endothelial genes induced at sites of inflammatory or immune responses reveals binding sites for the transcription factor nuclear factor kappa B (NF-kappa B). Endothelial cells express transcripts encoding the p50/p105 and p65 components of NF-kappa B and the rel-related proto-oncogene c-rel; steady state levels of these transcripts are transientl...

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