Introduction Autism is approaching the numbers of an epidemic. Past efforts have focused on identifying the genetic basis of Autism Spectrum disorders with minimal success. Recently, a lot of work is being carried out in Epigenetics, Nutrigenetics in order to analyse the cause of Autism Spectrum Disorders. The present paper reviews the various studies being conducted in this domain and provides...

Nutritional research is undergoing a remarkable transformation driven by new technological tools. Because of the complexity of the components present in food and how they may interact with the biochemical networks of living organisms, nutrition cannot be considered a reductionist discipline. More holistic approaches, which are capable of gathering comprehensive, high-throughput amounts of data,...

Bio-cultural adaptations to new foods played a key role in human evolution. The fossil record and sequence differences between human and chimpanzee genes point to a major dietary shift at the stem of human evolution. The earliest representatives of the human lineage diverged from the ancestors of chimpanzees because of their better adaptation to hard and abrasive foods. Bipedalism and modificat...

Advances in molecular and recombinant DNA technology have led to exquisite studies in the field of genetics and the recognition in a much more specific way, through DNA sequencing, of how unique each one of us is, and the extent to which genetic variation occurs. The importance of the effects of genetic variation has been extensively studied and applied by pharmacologists in drug development an...

BACKGROUND/AIMS Prostate cancer runs in families and shows a clear dietary involvement. Until recently, the key risk gene(s) have proved elusive. We summarise current understandings of nutrient-gene interactions in prostate cancer risk and progression. METHODS A MEDLINE-based literature search was conducted. RESULTS Hypothesis-directed candidate gene approaches provide plausible, albeit sta...

Epidemiological studies over the past 50 years have revealed numerous risk factors for atherosclerosis. They can be grouped into factors with an important genetic component and environmental factors, particularly diet, which is one of the major, constant environmental factors to which our genes are expose through life. When a gene is activated, or expressed, functionally distinct proteins are p...