BACKGROUND AND AIMS An increased number of circulating osteoprogenitor cells (OPCs) expressing bone-related proteins and the stem cell marker CD34 have been identified in women with postmenopausal osteoporosis, who also have stiffer arteries than nonosteoporotic subjects. We investigated whether an increased number of circulating OPCs underlies the association of osteoporosis with arterial stif...

T cells are known to develop in the thymus. However, molecular events that control the transition from hematopoietic progenitor cells in the bone marrow to T precursor cells seeded in the thymus remained poorly defined. Our recent report showed that osteocalcin (Ocn)-expressing bone cells in the bone marrow have major impact on T cell immunity by regulating T progenitor development in the bone ...

On-Chip Networks (OCNs) have been proposed to solve the complex on-chip communication problems. In Very Deep-Submicron era, OCN will also be affected by faults in chip due to technologies shrinking. Many researches focused on fault detection and diagnosis in OCN systems. However, these approaches didn’t consider faulty OCN system recovery. This paper proposes a scalable built-in self-recovery (...

Background Rheumatoid arthritis (RA) is a chronic inflammatory disease characterised by joint swelling, compression and synovial destruction, where inflammation bone destruction can lead to significant functional impairment. Recently, several studies have reported the identification of new biomarkers RA, such as osteoprotegerin (OPG), osteocalcin (OCN) osteopontin (OPN) [1] , all three which pl...

Due to the learning difficulties in mathematics education, a new teaching methodology have been proposed for its improvement. Difficulties indicate that students are not able properly deal with resolving calculations and/or problems. This research examines evolution of attitudes pre-service teachers’ (PSTs) toward when an open calculation based on numbers (OCN) method was followed flipped class...

This study investigated the effect of Computer-Aided Instruction on chemistry students’ achievement in organic chemical nomenclature Enugu Education zone State, Nigeria. One research question and one hypothesis guided study. The design adopted was quasi experimental, pretest-post test, non equivalent control design. sample for comprised 308 students (122 male 186 female) purposively sampled fro...

This study was aimed to explore the role of tanshinol in osteoblastic cells, and the role in vivo using an ovariectomized (OVX) rat model of osteoporosis. MC3T3-E1 cells were pretreated with 0-400 μg/mL tanshinol, and then cell viability, apoptosis, alkaline phosphatase (ALP) activity and the expressions of Collagen Type I Alpha 1 (Col1A1), Runt Related Transcription Factor 2 (Runx2) and osteoc...

Here, we aimed to investigate osteogenic differentiation of human adipose-derived stem cells (hASCs) in three-dimensional (3D) bioprinted tissue constructs in vitro and in vivo. A 3D Bio-plotter dispensing system was used for building 3D constructs. Cell viability was determined using live/dead cell staining. After 7 and 14 days of culture, real-time quantitative polymerase chain reaction (PCR)...

DESIGN The cytological diagnosis of oncocytic/Hurthle cell neoplasms (OCN) represents a challenge with which cytopathologists face up to in their practice. The majority of these lesions undergo surgery for a definitive characterization of the nature mainly due to their more aggressive behavior than other malignant follicular lesions. In this study, we aimed at the evaluation of the effective ma...