The spherical porous granules of octacalcium phosphate (OCP) and hydroxyapatite (HA) have the potential for applications in scaffolds bone regeneration. alpha-tricalcium were immersed a pH 5.0 buffer solution that contained 0.1 mM ascorbic acid (AscP), an osteogenesis-promoting drug, at 60 °C. This resulted fabrication AscP-loaded HA/OCP granules. OCP HA phases concentrated surface interior gra...

What are biominerals and how are they formed? It is usually assumed: (i) that the prototype for most apatitic biominerals is hydroxyapatite (OHAp), Ca5(PO4)3OH; and (ii) that the OHAp structure has been modified by the presence of impurity ions and vacancy defects in specific OHAp lattice sites. The usual answer, at least implicitly, to the second question is that the apatitic mineral is formed...

In vitro studies on interactions between amelogenins and calcium phosphate crystals are critical for elucidating biomineralization mechanisms of tooth enamel. This work was aimed at investigating the effects of native porcine amelogenins on octacalcium phosphate (OCP) crystal growth in a gelatin gel. We prepared OCP mineral discs by circulating calcium and phosphate solutions on the opposite en...

Octacalcium phosphate (OCP) is proving to be an important intermediary in the formation of tooth and bone mineral and various pathological calcifications. Before this mineral can form, its solubility product must be exceeded. Thus, a knowledge of its precise values under various conditions is required for a basic understanding of calcification processes. The methodology suitable for measuring t...