OBJECTIVE To determine whether there is a difference in disease severity between familial and sporadic primary open-angle glaucoma (POAG). METHODS A cross-sectional study design compared the distribution of Glaucoma Inheritance Study in Tasmania (GIST) severity scores of patients with genealogically confirmed familial POAG and those with sporadic POAG. The GIST severity scores provide a combi...

PURPOSE To understand the impact of socioeconomic status (SES) on the diagnosis of primary open-angle glaucoma (POAG) and primary angle closure glaucoma (PACG) in Taiwan. METHODS Subjects with glaucoma were identified from the National Health Insurance Research Database of year 2006, which included one million randomly selected insurants. Individuals who had ≥4 ambulatory visits within one ye...

purpose : to compare the ability of scanning laser polarimetry (gdx vcc), and optical coherence tomography (oct) to discriminate eyes with primary open angle glaucoma (poag) from normal eyes and to assess the relationship between their parameters methods : eighty-seven glaucomatous eyes of 87 patients and 25 normal eyes were enrolled. the mean age of patients and normal group were 54.96±18.34 a...

PURPOSE To determine the incidence and contribution of different types of glaucoma to blindness at Irrua Specialist Teaching Hospital, a suburban tertiary care hospital in Edo State, Nigeria. METHODS Medical records of all new patients with glaucoma who presented to the eye clinic of the hospital from June 2007 to May 2009 were reviewed. RESULTS Out of a total of 2,742 new patients seen ove...

PURPOSE To evaluate in different types of glaucoma frequency of family history of glaucoma (FHG), age at diagnosis, glaucoma risk in relatives, and acceptance rate of genetic glaucoma tests. To assess stage of visual field loss (VFL) in relation to FHG. METHODS Using standardized questions whether an ophthalmologist had found or excluded glaucoma or ocular hypertension (OH), 2170 patients wit...

PURPOSE To report the results of screening first degree relatives of persons identified with primary open angle glaucoma in a tertiary eye hospital glaucoma services. DESIGN A cross-sectional study of first degree relatives of persons with primary open angle glaucoma. MATERIALS AND METHODS First degree relatives of patients identified with primary open angle glaucoma were invited to partici...

 Primary open-angle glaucoma (POAG) is an idiopathic disorder in which the resistance to outflow through the trabecular meshwork gradually increases and the intraocular pressure (IOP) rises, causing irreversible damage to the optic nerve  POAG is the second most common cause of vision loss in the U.S.  Usually asymptomatic until advanced visual field loss has occurred; less than 50% of those...

Although glaucoma is a major global cause of blindness, the lack of a uniform definition of the disease in its different forms makes it difficult to assess its public health impact. By considering the common features of glaucoma, we have analysed available data on the three main forms of the disease: congenital/hereditary glaucoma, primary open-angle, and primary angle-closure glaucoma. A simpl...

Glaucomas are a heterogeneous group of eye conditions with manifestation from as early as birth to very late age of onset in life. The primary type of these conditions affecting children and juveniles are less frequent, but the prevalence of glaucomas affecting older people of > or = 70 years progressively rises to approximately 5%. The molecular genetics of three types of glaucoma have been th...