BACKGROUND Human papillomavirus (HPV), the causal agent of cervical cancer, appears to be involved in the etiology of cancer of the oral cavity and oropharynx. To investigate these associations, we conducted a multicenter case-control study of cancer of the oral cavity and oropharynx in nine countries. METHODS We recruited 1670 case patients (1415 with cancer of the oral cavity and 255 with c...

Of all Cancers, Oral cancer is one of the most typical cancers in world. has delayed clinical detection, poor prognosis, without specific biomarkers, and expensive therapeutic methods. This study aims to explain basic aspects oral focuses on squamous cell carcinoma cavity. The duration detection depends amount tobacco usage individual. In this study, we have presented stochastic models for onse...

background and objective: different mechanisms may lead to the development of soft tissue tumor-like lesions in the oral cavity. many of these lesions can be identified as specific entities on the basis of their histopathological features and are divided into fibrous, vascular, and giant cell types. the purpose of this study was to establish the relative prevalence of the different histopatholo...

introduction: peripheral reactive lesions of soft tissue are common oral lesions that dentists face during routine examinations. diagnosis and development of a treatment plan is difficult if dentists are not aware of the prevalence and clinical symptoms of these lesions. the frequency of these lesions differs across various populations. the aim of this study was to determine the frequency and d...

oral cancer is considered a great threat to public health. tongue cancer accounts for nearly 30% of all oral cancers and usually seen in 50 to 60 year old men. oropharyngeal cancers account for 3% of all cancers in iran; as reported in 2003. the present study was designed to assess the epidemiologic and clinicopathologic characteristics of tongue cancer patients in two tehran's referral univers...

Many types of cancers develop in the oral and maxillofacial region. Squamous cell carcinoma is the most common cancer and constitutes over 90 percent of these tumors. Malignant transformation is a genetic process, which later makes a phenotyping change at the cellular level. Some cancers such as oral squamous cell carcinomas (OSCCs) develop from pre-malignant lesions and conditions. Despite adv...

Secondary oral cavity neoplasms are rare. We describe a case of an indurated, nonulcerating gingival lesion in a 59-year-old nonsmoking man with no family history of lung cancer. The lesion was the presenting symptom of metastatic lung adenocarcinoma. Reviewing the literature, we find that primary lung cancer among men is one of the most common cancers to metastasize to the oral cavity. Renal a...

Background: Portulaca oleracea as a herbal plant has been widely used in traditional medicine to cure many diseases. The therapeutic effects of this plant are exerted through its active ingredients with antioxidant properties. It has been shown that this plant may have cytotoxic effects on cancer cells. In the present study, cytotoxic effects of aqueous extract of Portulaca oleracea on oral cav...

Background The majority of patients diagnosed with oropharyngeal squamous cell cancer (OPSCC) are due to HPV infection. At present, there are no reliable tests for screening HPV in patients with OPSCC. The objective of this study was to assess the Cobas® HPV Test on oral rinse specimens as an early, non-invasive tool for HPV-related OPSCC. Methods Oral rinse specimens were collected from 187 ...