The purpose of this study was to determine the prevalence of oral lichen planus in a population of patients with diabetes mellitus compared with a control population and to determine if patient medications had any influence on the presence of such lesions. Two hundred seventy-three patients with diabetes and an identical number of age-, gender- and race-matched controls were examined for clinic...

Introduction: Malondialdehyde (MDA) is a useful determinant to show high level of lipid peroxidation which lead to impaired cell function. Previous studies have mentioned there is a relationship between high oxidative stress and low anti-oxidant activity in patients with oral lichen planus. The aim of this study was to evaluate serum level of Malondialdehyde as an indicator of oxidative stress ...

Background: Lichen planus is a chronic inflammatory disease ofunknown etiology that may involve mucocutaneous tissues. Themain aim of our study was to evaluate the frequency of oral andgenital lichen planus in men and women affected by skin lesions.Method: A total of 132 patients with clinical and histopathologicaldiagnosis of lichen planus were evaluated for oral and genitalinvolvement. All da...

Le lichen blaschko-linéaire constitue une forme rare (0,5 %) du lichen plan dont l'âge moyen de survenue est de 50ans. Il est plus fréquent chez l'homme. Sa disposition linéaire en dehors du phénomène de Koebner serait due au mosaicisme génétique responsable de la présence d'un clone kératinocytaire capable de réagir sous l'effet de facteurs immunogènes, exogènes ou infectieux. Le traitement re...

background and aims. the purpose of this study was to determine efficacy of 19% elaeagnus angustifolia (ea) topical gel in the treatment of symptomatic oral lichen planus. materials and methods. patients with symptomatic oral lichen planus referring to the department of oral medicine, faculty of dentistry at shahid beheshti university of medical sciences were asked to participate in the study. ...

Erasmus Wilson (1869) described lichen planus for the first time.1 It is relatively common dermatological disorder occurring on skin and oral mucous membrane.2 It refers to lace like pattern produced by symbolic algae and fungal colonies on the surface of rocks in nature (Lichens). Prevalence of lichen planus in general population is about 0.9 to 1.2% and prevalence of oral lichen planus is rep...

Lichen planus is a chronic, inflammatory, autoimmune disease that affects the skin, oral mucosa, genital mucosa, scalp, and nails. Lichen planus lesions are described using the six P's (planar [flat-topped], purple, polygonal, pruritic, papules, plaques). Onset is usually acute, affecting the flexor surfaces of the wrists, forearms, and legs. The lesions are often covered by lacy, reticular, wh...

introduction: oral lichen planus (olp) is a common mucocutanous disorder with unknown etiology. while current data suggest that oral lichen planus is a cell-mediated autoimmune disease, it might be associated to s+100, cd+4 and cd+8 cells. because of differential diagnosis of olp and oral lichenoid lesion (oll) is usually difficult this study was designed to compare any probable immunohistochem...

statement of the problem: lichen planus is a mucocutaneous disease that is relatively common in middle aged individuals. some studies have shown that oral lichen planus has a potential to progress to squamous cell carcinoma.p21 is a cyclin-dependent kinase inhibitor that regulates the cell cycle, thus it acts as an inhibitor in cell proliferation. purpose: this study was aimed to evaluate and c...

Lichen planus is a fairly distinctive, chronic, immunologically mediated mucocutaneous disease, of uncertain etiology that was first described as a disease of the skin that can also affect mucosal surfaces, including those that line the oral cavity. The prevalence of LP in the general population is of the order of 0.9 to 1.2%. It is stated that approximately 40% of lesions occur on both oral an...