Objective. A total of 1112 pediatric outpatient sedations, by either nitrous oxide–oxygen inhalation (N2O) or oral midazolam, administered over a 10-year period were reviewed. Patient responses and outcomes were evaluated to ascertain the safety of these sedation techniques. Study design. A total of 819 patients were included in this study. Patient health status, age, weight, behavior, treatmen...

Background and Objectives: The present study was conducted to assess the effects of low dose Midazolam with Propofol and Propofol alone during minor oral and maxillofacial surgeries; to evaluate the level of sedation, post-operative amnesia, and condition of the patient during surgery, patient satisfaction and opinion. Material and Methods: Fifty ASA Grade I and II patients were randomly alloca...

PURPOSE To evaluate the safety and usefulness of the use of oral sedation with midazolam (15 mg) in patients submitted to blepharoplasty. METHODS Randomized double-blind prospective study of 42 patients (surgical risk ASA I and II) divided into three groups of 14 patients each: Group M (midazolam 15 mg), group P (placebo) and group SM (no medication). All patients were evaluated according to ...

abstract   background: voiding cystourethrography (vcug) is a distressing procedure for children. conscious sedation with any drug that its dose would not influences the procedure is preferred. the aim of this study was to assess the effectiveness of conscious sedation using oral midazolam in children undergoing vcug.   methods: from november 2008 to october 2009 period, 93 patients (68 girls a...

BackgroundAlthough midazolam and ketamine are widely administrated as oral premedications for children, only a few studies have investigated the cardiovascular, respiratory and sedative effects of these drugs in children with congenital heart disease (CHD). MethodsWe compared three methods of administering midazolam and ketamine and a combination of these two drugs as an oral premedication in 1...

In a randomized, double-blind, placebo-controlled study, the safety, efficacy and feasibility of oral midazolam premedication in children were evaluated in an ambulatory surgery unit. Eighty unmedicated children (ASA PS I or II, ages 1-6 yr) were randomly assigned to one of four groups receiving midazolam 0.5, 0.75, or 1.0 mg.kg-1 or a placebo 30 min before separation from parents. Heart rate, ...

PURPOSE This study was undertaken to compare the effectiveness of oral diazepam and midazolam in sedating autistic patients during dental treatment. METHODS The treatment regimen consisted of nitrous oxide/oxygen inhalation in conjunction with oral administration of either diazepam 0.3 mg/kg or midazolam 0.5 mg/kg in a cross-over design study of 13 subjects aged 5.8 to 14.7 years. A drug was ...

Background and aims. There are several known sedative drugs, with midazolam and ketamine being the most commonly used drugs in children. The aim of this study was to compare the effect of intranasal and oral midazolam plus ketamine in children with high levels of dental anxiety. Materials and methods. A crossover double-blind clinical trial was conducted on 23 uncooperative children aged 3-6 (n...

background: selecting the best medication for upper gi endoscopy in children is a challenging issue. the goal of this study was to compare the effects of oral and intravenous midazolam for upper gastrointestinal endoscopy (ugie) on children. methods: in this randomized clinical trial study conducted in amirkola children's hospital, 110 children were randomly assigned to oral or intravenous...

BACKGROUND The minimum time interval between administration of oral midazolam and separation of children from their parents that ensures good anterograde amnesia has not been previously determined. This is of particular importance in a busy operating room setting where schedule delays secondary to midazolam administration may not be tolerated. METHODS Children (n = 113) undergoing general ane...