Toluene is a commonly used volatile organic chemical in industry and is the most often chosen illicit substance among volatile substance abusers. Studies involving healthy volunteers suggest that ethanol consumption inhibits toluene metabolism, thus increasing its blood levels. In this study, a lethal case of combined ethanol consumption and toluene inhalation has been reported. Our case was a ...

research findings have shown that birth order and season of birth are related to some of the mental disorders such as schizophrenia, mood disorders. autism, attention deficit disorder with hyperactivity and substance abuse, and these disorders are related to dopamine level. a retrospective study was designed to investigate 130 substance abusers (119 males and 11 females) which were treated duri...

..................................................................................................................ix INTRODUCTION .....................................................................................................1 Past Typologies for Classifuing Substance Abusers ....................................1 Personality and Substance Use: Substance Use Risk Profile Scale ...............

Organic cation transporters play a critical role in the elimination of therapeutic compounds in the liver and the kidney. We used computational quantitative structure activity approaches to predict molecular features that influence interaction with the human ortholog of the organic cation transporter (hOCT1). [(3)H]tetraethylammonium uptake in HeLa cells stably expressing hOCT1 was inhibited to...

BACKGROUND AND PURPOSE The human organic cation transporter-1 (hOCT1) is a polyspecific transporter that plays a role in drug distribution, metabolism and excretion. Previous studies have demonstrated that hOCT1 binding can be stereoselective, but the mechanism for stereochemical recognition has not been described. The purpose of this study was to develop a pharmacophore model to describe stere...

A corrosion inhibitor was widely used to improve resistance of steel bar in reinforcement concrete structure. kind multi-component inhibitor, which is composed organic and inorganic substances, developed this research. This comparatively studied with various other inhibitors by using open circuit potential (OCP), electrochemical impedance spectroscopy (EIS), cyclic voltammetry (CV) methods. The...