EDITORIAL article Front. Physiol., 05 July 2023Sec. Invertebrate Physiology Volume 14 - 2023 | https://doi.org/10.3389/fphys.2023.1248654

The vestibular system is a sensory system that is critically important in humans for gaze and image stability as well as postural control. Patients with complete bilateral vestibular loss are severely disabled and experience a poor quality of life. There are very few effective treatment options for patients with no vestibular function. Over the last 10 years, rapid progress has been made in dev...

Widdowson, E. M., Crabb, D. E., and Milner, R. D. G. (1972). Archives of Disease in Childhood, 47, 652. Cellular development of some human organs before birth. The total amount of DNA and the protein/DNA ratio have been measured in the kidneys, heart, liver, and gastrocnemius muscles of 56 human fetuses and newborn infants of 13-42 weeks' gestational age. The total amount of DNA in each organ a...

The XIV Workshop on the Development and Function of Reproductive Organs was held in Rome, from 14-17 September, 2008, at the Congress Centre of the University of Tor Vergata of Villa Mondragone (Rome, Italy). The Workshop was conceived to be a survey of the events from the formation of the gamete precursors, the primordial germ cells, to the development of the preimplantation embryo through fem...

There is striking variation in the incidence of cancer in human organs. Malignant tumors are common in the colon and breast but rare in the heart and small bowel. The uterus frequently develops benign fibroid tumors but uterine cancers are relatively rare. The organ-specific difference in cancer prevalence has been explained primarily by the relative roles of intrinsic and extrinsic risk factor...

Dlgh1 (discs large homolog 1) is a mammalian homolog of the Drosophila tumor suppressor Discs large 1, and is a member of the membrane-associated guanylate kinase (MAGUK) scaffolding proteins that contain three PSD-95/Dlg/ZO-1 (PDZ) domains. Discs large 1 is involved in epithelial polarization and cell-cell adhesion complex formation during Drosophila development. However, the functions of Dlgh...