In oncogenic osteomalacia (OOM), fibroblast growth factor 23 (FGF23) induces renal phosphate wasting and inhibits the appropriate increase of calcitriol. A patient suffering from OOM is described. Serum calcium, phosphate, biointact parathyroid hormone and intact FGF23 as well as the calcitriol and 24,25-vitamin D levels were measured before and after tumour removal. The clinical approach to a ...

Aufgrund eines Mangels an geeigneten Lernmaterialien zum OOM in der Sekundarstufe wurde ein „Didaktisches System für OOM“ entwickelt, um diesem zu begegnen. Die System-Komponente „Aufgabenklassen“ dient u.a. dazu, für vielfältige Lehr-Lern-Situationen angemessene Problemstellungen zu entwickeln. Die Einbettung dieser Aufgabenklassen in drei Informatikgrundkurse der Jgst. 11 und 12 wird exemplar...

OBJECTIVE Oncogenic hypophosphatemic osteomalacia (OOM) is a rare disease characterized by hypophosphatemia, inappropriately low levels of circulating 1,25-dihydroxyvitamin D(3) and osteomalacia. The disease is most commonly caused by benign mesenchymal tumors that produce, among several other factors, fibroblast growth factor-23 (FGF-23). Current evidence thus suggests that this protein has an...

We treat observable operator models (OOM) and their non-commutative generalisation, which we call NC-OOMs. A natural characteristic of a stochastic process in the context of classical OOM theory is the process dimension. We investigate its properties within the more general formulation, which allows to consider process dimension as a measure of complexity of non-commutative processes: We prove ...

In oncogenic osteomalacia (OOM), a tumor produces an unknown substance that inhibits phosphate reabsorption in the proximal tubules. This causes urinary phosphate wasting and, as a consequence, hypophosphatemic osteomalacia. To characterize this poorly understood biological tumor activity we generated aqueous extracts from several OOM tumors. Extracts from three of four tumors inhibited, dose- ...

in recent years, formal methods have been used as an important tool forperformance evaluation and verification of a wide range of systems. in the viewpoints of engineers and practitioners, however, there are still some major difficultiesin using formal methods. in this paper, we introduce a new formal modelinglanguage to fill the gaps between object-oriented programming languages (oopls)used by...

SERVICE ORIENTED ARCHITECTURE ADOPTION IN E-EDUCATION SYSTEM