background: recent studies have showed conservative management in selective patients with borderline and malignant ovarian tumors is safe; therefore this management is considered in patients with ovarian tumor who desire to preserve fertility. objective: this study has been performed to evaluate the clinical outcome and fertility in patients with ovarian tumors who were treated conservatively. ...

Background: Infertility is an important and common problem in couples that needs to assisted reproductive technology (ART) or the other drug therapies. Infertility has been known as a risk factor for ovarian cancer, breast cancer and endometrial cancer but there is a question about the relationship of these cancers to infertility itself or drugs and methods of infertility treatment. Materials a...

Ovarian cancer is the most lethal gynecologic malignancy. The surface epithelial tumor is the most common type of ovarian cancer. Among these, the mucinous tumors account for 10-15% of ovarian tumors. Mucinous ovarian tumors are among the most difficult ovarian neoplasms for surgical pathologists to interpret. Mucinous tumors sometimes coexist with other surface epithelial tumors. Therefore, ma...

background: the activity and toxicity of etoposide in women with recurrent ovarian cancer was evaluated in a case series of women with recurrent ovarian cancer who had measurable disease, methods: all patients had plior platinum-based chemotherapy and developed progressive disease, etoposide was given as 50mg/day for 21 days every 4 weeks until progression of disease or prohibitive toxicity, be...

current protocols for cancer treatment could lead to the failure of ovarian function and subsequent infertility in women. therefore, utilizing ways to preserve fertility in these individuals seem to be essential. in this review, the full-text of articles which were accessible and had been published during 1976 to 2009 about different methods of female fertility preservation were collected and s...

(Abstracted from J Clin Oncol 2022; doi: 10.1200/JCO.21.01900) Ovarian cancer is the deadliest gynecologic because of its nonspecific symptom presentation and lack early detection or prevention strategies. Chronic inflammation has been demonstrated to play a key role in molecular mechanisms driving ovarian cancer.

Ovarian Cancer Treatment In article number 2204436 by Daniel L. Marks, Oleh Taratula, and co-workers, follistatin mRNA delivered lipid nanoparticles targets ovarian cancer clusters dispersed in the peritoneal cavity of mice. When combined with platinum chemotherapy, proposed treatment may allow complete cytoreduction, enhance resilience to iatrogenic burden chemotherapeutic intervention, increa...