Objective(s): Progestrone is a prequisite for pre-implantation angiogenesis and induce decidual angiogenesis. It is unknown the effect of progestrone administration on the endometrium of hyperstimulated mice at pre-implantation time. Material and Methods: Adult female NMRI mice were divided in three groups [control group, ovarian stimulated group and progestrone treated mice after ovarian stimu...

The standard goal of all fertility treatments is the improvement of pregnancy rates in infertile patients. Within the last 20 years, ovulation induction has contributed to the success of assisted reproduction techniques e.g. in vitro fertilization (IVF) and embryo-transfer (ET). The efficacy of these techniques depends on a personalized protocol of controlled ovarian hyperstimulation (COH) and ...

background: the ability of the ovary to respond to exogenous gonadotrophin stimulation and development of several follicles is essential in assisted reproductive technology. neither age and regularity of menses nor follicular phase fsh and estradiol concentrations are reliable predictors of ovarian response. day 3 serum inhibin-b level, during induction ovulation, has been proposed as a predict...

background: despite extensive progress in ivf techniques, one of the most difficult problems is the variability in the response to controlled ovarian hyperstimulation (coh). recent studies show the effects of individual genetic variability on coh outcome. objective: to evaluate the correlation between lhβ g1502a polymorphisms in exon 3 of the lh gene and ovarian response to coh. materials and m...

Ovarian stimulation is applied in the clinic to restore mono-ovulatory cycles in anovulatory women (ovulation induction) or to induce the development of multiple dominant follicles for assisted reproduction. Ovarian response is the endocrine and follicular reaction of the ovaries to stimulation. Achieving an appropriate ovarian response to anti-estrogens or exogenous gonadotrophins is central t...

objective: to compare the pregnancy outcomes achieved by in vitro fertilization (ivf) between minimal stimulation and conventional antagonist protocols in poor ovarian responders (pors). materials and methods: in this randomized controlled trial, 77 pors undergoing ivf were selected and divided into two groups. first group was the minimal stimulation group (n = 42) receiving 100 mg/day clomiphe...

background: c-reactive protein (crp) can be increased after hormonal stimulations. the changes of crp might affect the success of in-vitro fertilization (ivf). objective: the aim of this study was to determine the possible relationship between the serum crp level and outcome of controlled ovarian stimulation, and pregnancy rate in patients undergoing ivf or intra cytoplasmic sperm injection (ic...

Background: With the recent development of recombinant gonadotropins (FSH and LH), it has become possible to further adjust the stimulation protocol according to the expected needs of the patient. In this respect, the possible beneficial role of exogenous LH activity supplementation for stimulated ART cycles has received increasing attention. According to the two-cell, two- gonadotropin theory,...