Cerebral metabolism is compartmentalized between neurons and glia. Although glial glycolysis is thought to largely sustain the energetic requirements of neurotransmission while oxidative metabolism takes place mainly in neurons, this hypothesis is matter of debate. The compartmentalization of cerebral metabolic fluxes can be determined by (13)C nuclear magnetic resonance (NMR) spectroscopy upon...

Occupational exposure to air pollution induces oxidative stress and prolonged exposure increases susceptibility to cardiovascular and respiratory diseases in several working groups. Biofluid of these subjects may reflect perturbed metabolic phenotypes. In this study we carried out a comparative molecular profiling study using parallel biofluids collected from subjects (n = 85) belonging to auto...

Here, we first report the 2′-acyloxy-1,3-dicarbonyl compound construction in a three-component oxidative reaction of alkyl ketene dimer with cyclic diacyl peroxide and trimethyl orthoformate. The discovered synthesis allows us to form 2′-functionalized 1,3-dicarbonyl compounds instead common 2-functionalized moiety. between 4-butylidene-3-propyloxetan-2-one cyclopropyl malonoyl proceeds presenc...

The textural, structural, morphological, and acidic properties of TiO2/Al-ZSM-12 zeolite synthesized viathe hydrothermal method using methyltriethylammonium chloride as a template were studied in this study. structure, size, shape the crystallites, acidity materials investigated detail following methods: XRD, low-temperature nitrogen adsorption–desorption, XRF, FTIR, Raman spectroscopy, DRS UV–...

Antipyrine is a useful probe to evaluate variation of in vivo activities of oxidative hepatic drug-metabolizing enzymes. Here we describe a new approach using C labeling and NMR spectroscopy for the direct and simultaneous detection of all phase I and phase II metabolites of antipyrine in rat urine. [C-methyl-C]Antipyrine was synthesized and administered orally to rats (100 mg/kg), and the 0to ...

This study investigates the comparative impact of inherently different biomass and coal ashes on laboratory pilot scale degradation 30 wt% aqueous monoethanolamine (MEA), relevant to post-combustion CO2 capture. Thermal oxidative experiments were carried out at 135 °C 40 respectively with loading (0.5 molCO2/molMEA), without presence ash. Nuclear magnetic resonance (NMR) data is provided for ma...

Jatropha curcas oil is one of interesting renewable resources for preparation biolubricants. However, direct application this as a biolubricant restricted due to its low oxidative stability. This drawback can be overcome by molecule structural redesign through chemical modification process at unsaturated functional groups. was modified via epoxidation, ring opening and esterification processes....

Abstract Plasma fibrinogen is an important coagulation factor and susceptible to post-translational modification by oxidants. We have reported impairment of fibrin polymerization after exposure hypochlorous acid (HOCl) increased methionine oxidation in severely injured trauma patients. Molecular dynamics suggests that poses a mechanistic link between oxidative stress through protofibril lateral...