Five lactating Holstein cows with ruminal and duodenal cannulas were used in a 5 x 5 Latin square to determine the site of mineral absorption and effects of sources and amount of dietary fat on apparent absorption. Cows were fed (DM, 17.4 +/- .8 kg/d) chopped alfalfa hay, alfalfa haylage, corn silage, and concentrate at 1:1:1:2 (DM) at 12-h intervals. Calcium salts of palm fatty acid distillate...

BACKGROUND Iron absorption in humans is highly variable even after iron status and dietary components that influence iron absorption are controlled for. Inherited factors may help explain this variance. OBJECTIVE Our objective was to compare nonheme-iron absorption from a noninhibitory, stable-isotope-labeled test meal in preschool-aged children and their mothers. DESIGN We provided 72 test...

BACKGROUND Phytic acid in cereal-based and legume-based complementary foods inhibits iron absorption. Low iron absorption from cereal porridges contributes to the high prevalence of iron deficiency in infants from developing countries. OBJECTIVE The objective was to measure the influence of phytic acid degradation on iron absorption from cereal porridges. DESIGN An exogenous phytase was use...

Recent studies showed that P-glycoprotein (P-gp) increases the portal bioavailability (FG) of loperamide by sparing its intestinal first-pass metabolism. Loperamide is a drug whose oral absorption is strongly attenuated by intestinal P-gp-mediated efflux and first-pass metabolism by cytochrome P450 3A (CYP3A). Here the effect of the interplay of P-gp and Cyp3a in modulating intestinal first-pas...

BACKGROUND 1) To evaluate calcium absorption in infants fed a formula containing prebiotics (PF) and one without prebiotics (CF). 2) To compare calcium absorption from these formulas with a group of human milk-fed (HM) infants. METHODS A dual tracer stable isotope method was used to assess calcium absorption in infants exclusively fed CF (n = 30), PF (n = 25) or HM (n = 19). Analysis of varia...

The effect of chronic alcohol ingestion and folic acid deficiency on iron absorption in rabbits was studied. Iron absorption was measured in a whole-body counter using Fe. and plasma iron turnover (PIT) was simultaneously determined with ‘Fe. One group was given a 20% ethanol solution for 2 or 6 mo. There was no significant differonce in iron absorption (p > 0.50). while PIT was reduced (p < 0....

Sixteen patients (aged 3.5-14.3 years) with normal jejunal mucosa, originally diagnosed as having coeliac disease at least 18 months before, were started on gluten challenge. The 'end point' of challenge was significant deterioration in jejunal mucosa morphologically and morphometrically. Studies carried out both before and after challenge included intestinal absorption of D-xylose and glucose,...