نتایج جستجو برای: parathyroid cancer

تعداد نتایج: 923803  

Journal: :Head & neck 2004
Naifa L Busaidy Camilo Jimenez Mouhammed Amir Habra Pamela N Schultz Adel K El-Naggar Gary L Clayman Joshua A Asper Eduardo M Diaz Douglas B Evans Robert F Gagel Adam Garden Ana O Hoff Jeffrey E Lee William H Morrison David I Rosenthal Steven I Sherman Erich M Sturgis Steven G Waguespack Randal S Weber Kelly Wirfel Rena Vassilopoulou-Sellin

PURPOSE Because parathyroid carcinoma is rare, clear consensus is not available regarding the optimal management of patients with this condition. Treatment strategies generally derive from clinical and anecdotal experiences. We report our experience with this entity. METHODS We included all patients with parathyroid carcinoma seen at The University of Texas M. D. Anderson Cancer Center since ...

Journal: :The Medical journal of Australia 2013
Samantha E Bowyer Alison M White David T Ransom John A Davidson

1 Department of Medical Oncology, We report a case of inoperable metastatic parathyroid carcinoma involving lifethreatening hypercalcaemia that failed to respond to standard therapy. Our review of available therapeutic modalities showed a paucity of evidence to guide management of patients with these rare tumours. This is the first report of the treatment of malignant hypercalcaemia secondary t...

2016
Bong Kyun Kim Jina Lee Woo Young Sun

About 20%-30% of all cases of multiple endocrine neoplasia type 2A (MEN 2A) is accompanied by primary hyperparathyroidism. These patients undergo parathyroidectomy and, if needed, autotransplantation. In rare cases, autotransplanted parathyroid tissues can cause hypoparathyroidism due to failure of transplantation or hyperparathyroidism due to proliferation of the transplanted tissue. A 68-year...

Journal: :Cancer research 2003
Steven K Libutti Judy S Crabtree Dominique Lorang A Lee Burns Chiara Mazzanti Stephen M Hewitt Sarah O'Connor Jerrold M Ward Michael R Emmert-Buck Alan Remaley Marshall Miller Ewa Turner H Richard Alexander Andrew Arnold Stephen J Marx Francis S Collins Allen M Spiegel

The inactivation of the MEN1 tumor suppressor gene in patients leads to a constellation of changes in endocrine tissues, including parathyroid neoplasia, pituitary adenomas, pancreatic neuroendocrine tumors, and carcinoids. To study the pathophysiological consequences of the deletion of the MEN1 gene, we set out to create a mouse model of hyperparathyroidism resulting from the deletion of the M...

2016
Chenlei Shi Bo Tian Shengze Li Tiefeng Shi Huadong Qin Shaoyan Liu

The aim of this study was to determine the effects of nanocarbon particles in combination with meticulous capsular dissection on enhancing the identification and protecting the function of parathyroid glands in thyroid cancer surgery.The data of 97 patients with papillary thyroid tumors diagnosed and treated at the Second Affiliated Hospital, Harbin Medical University between January 2014 and F...

Primary hyperparathyroidism (pHPT) is defined by the excess level of parathyroid hormone (PTH). Parathyroid adenoma is responsible for about 80% of all pHPT. Parathyroid adenoma with cystic feature and atypical pathology is recognized as a rare entity. Technetium-99m methoxy isobutyl isonitrile ([99mTc]Tc-MIBI) scintigraphy has favorable detection rate for ectopic gland as well as th...

2016
Charles Meltzer Marc Klau Deepak Gurushanthaiah Hari Titan Di Meng Linda Radler Alvina Sundang

Objective. To develop a predictive model for the risk of complications after thyroid and parathyroid surgery. Study Design. Case series with planned chart review of patients undergoing surgery, 2007-2013. Setting. Kaiser Permanente Northern California and Kaiser Permanente Southern California. Subjects and Methods. Patients (N = 16,458) undergoing thyroid and parathyroid procedures were randoml...

Parathyroid carcinoma is very rare, with only a few documented cases. Hence, metastatic lesions are infrequently documented on scintigraphic imaging. We present a case of a 63-year-old female presenting with elevated serum levels of ionized calcium and parathyroid hormone (PTH) who was referred to our department for a parathyroid scan with SPECT/ CT. Parathyroid scintigraphy showed a focus of i...

Mohsen Saghari Seyed Rasoul Zakavi,

Thirty one patients with biologic and clinical diagnosis of hyperparathyroidism were submitted to thalium-technetium scan prior to exploration of the neck. Scan findings were compared with the pathologic results. Surgical exploration of the neck showed a parathyroid adenoma in 24 patients, parathyroid carcinoma in one patient, normal parathyroid in another patient and parathyroid hyperplasia in...

2017
Rodrigo Arrangoiz Fernando Cordera David Caba Manuel Muñoz Juarez Eduardo Moreno Enrique Luque de Leon Manuel Muñoz

Parathyroid adenomas are a very common endocrine entity, whereas parathyroid carcinomas (PC) are extremely rare. With an estimated incidence of 0.015 per 100,000 population and an estimated prevalence of 0.005% in the United States, parathyroid cancer is one of the rarest of all human malignancies. PC is an extremely rare cause of primary hyperparathyroidism (PHPT). Men and women are equally af...

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