with a normal fetus and placenta. Twin pregnancies with partial hydatidiform mole coexisting with a live fetus are rarely reported, since fetuses identified with partial mole are generally triploid and tend to die in the first trimester.1,3,4 Hydatidiform mole with live fetus is associated with the risk of many maternal and fetal complications such as vaginal bleeding, preeclampsia, thromboembo...

Background Distinction of hydatidiform moles (HMs) from non-molar abortions and sub-classification of HMs are important for clinical practice; yet, diagnosis based solely on morphology is affected by interobserver variability. The objective of this study was to determine the role of DNA flow cytometry in distinguishing molar from non-molar pregnancies. MaterialsAndMethods This retrospective stu...

Histopathological assessment and flow cytometric analyses were carried out on 32 placentas (representative of each trimester) and 88 molar pregnancies. Three first trimester placentas were triploid, and the remaining 29 placentas were diploid. Of the 88 cases originally diagnosed as molar pregnancies, 26 were triploid (two complete moles, 20 partial moles, and four hydropic abortions); 59 were ...

background: hydatidiform mole is an important obstetric problem which can result in harmful and serious outcomes. in this study, an attempt was made to determine the proportion of hydatidiform mole in prenatal clinics of iran university of medical sciences (iums) to find the precise frequency of this disease. methods: between january 2012 and january 2013, all women who immediately after positi...

AIM To determine the potential value of interphase cytogenetic and argyrophilic nucleolar organiser region (AgNOR) analyses in the diagnosis and classification of hydatidiform moles. METHODS Serial tissue sections from 37 hydatidiform moles, histologically classified as 11 complete and 15 partial, and from 11 hydropic abortuses were examined by in situ hybridisation using digoxigenin labelled...

BACKGROUND: The aim of this population-based retrospective study was to evaluate the trend in the incidence of molar pregnancy. METHODS: Questionnaires about the occurrence of hydatidiform mole were mailed to all clinics and hospitals in Chiba Prefecture between 1974 and 2000. The diagnosis of hydatidiform mole was based on the post-operative morphological and/or pathological ®ndings. Data of l...

Gestational trophoblastic disease describes a number of gynaecological tumours that originate in the trophoblast layer, including hydatidiform mole (complete or partial), placental site trophoblastic tumour, choriocarcinoma and gestational trophoblastic neoplasia (GTN). Invasive moles are responsible for most cases of localized GTN. Two cases of GTN previously reported in the literature exhibit...

p a twin pregnancy with a complete hydatidiform mole with a coexistent foetus (chmf) is a rare condition that typically results in poor pregnancy outcomes. for patients with refractory vaginal bleeding, termination of pregnancy is more appropriate. however, unified methods for termination remain to be explored. in the present study, we reviewed the termination measures in four cases of twin pre...