precision, bolus injection system to study the effect of regional deposition of fine particulate matter (PM) within the human respiratory system and to investigate the optimal conditions for inhaled drug delivery. In contrast to existing methods, the new system computes parameters necessary and injects PM into breath cycles by a process of dynamic breath pattern analysis and statistical data re...

hydrogels are introduced to modem medicine as novel materials suitable for a variety ofbiomedical applications. studying hydrogels as novel biomaterials has become a fast-developingand exciting research field during the last two decades. these interesting biomaterials have found awide range of application including contact lenses, vehicles for drug delivery and scaffold in tissueengineering and...

The field of specific drug delivery is an expanding research domain. Besides the use of liposomes formed from various lipids, natural and synthetic polymers have been developed to prepare more efficient drug delivery systems either under macromolecular prodrugs or under particulate nanovectors. To ameliorate the biocompatibility of such nanocarriers, degradable natural or synthetic polymers hav...

The uses of particulate drug delivery systems covers all areas of medicine such as cardiology, endocrinology, gynecology, immunology, pain management, oncology and molecular biology. Microsphere is already having an impact on products as diverse as novel foods, medical devices, chemical coatings, personal health testing kits, sensors for security systems, water purification units for manned spa...

BARRIER PROPERTIES OF MUCUS Hasan M. Yildiz, Chemical Engineering, Northeastern University Mucus, a complex network consisting of microand nano-scale fluid-filled domains formed via mucin glycoprotein interactions, provides a barrier through which nutrients and orally delivered drugs must penetrate before entering the circulatory system. Mucus provides a significant, yet poorly characterized ba...

Nanotechnology is providing solutions several pharmaceutical drug delivery issues. With the emergence of nanotechnology, researchers become more interested in studying the unique properties of nanoscale materials. Nanoparticles are attractive tool in pharmaceutical and biomedical fields. These particulate systems have been used as a physical approach to alter and improve the pharmacokinetic and...

Mucoadhesive delivery systems offer several advantages over other oral controlled release systems by virtue of prolongation of residence time of drug, its targeting, and localization of the dosage form at a specific site. These advantages include bypass of first pass metabolism of the drug and hence more concentration of the drug is available for absorption. Mucoadhesion occurs between two surf...