نتایج جستجو برای: pathogenicity group
تعداد نتایج: 995791 فیلتر نتایج به سال:
Increasing antibiotic resistance urgently requires novel therapeutic options to combat bacterial infections. The anti-virulence therapy selectively intervening with pathogenicity without affecting bacterial viability is such a strategy to overcome resistance. We consider the virulence regulator PqsR as an attractive target in the human pathogen Pseudomonas aeruginosa, and recently discovered th...
Germline inactivating variants in BRCA1 lead to a significantly increased risk of breast and ovarian cancers in carriers. While the functional effect of many variants can be inferred from the DNA sequence, determining the effect of missense variants present a significant challenge. A series of biochemical and cell biological assays have been successfully used to explore the impact of these vari...
Horizontal transfer of mobile genetic elements within Staphylococci is of high biomedical significance as such elements are frequently responsible for virulence and toxic effects. Staphylococcus-encoded repressor proteins regulate the replication of these mobile genetic elements that are located within the so-called pathogenicity islands. Here, we report structural and functional characterizati...
Attaching and effacing (AE) bacteria are a diverse group of gastrointestinal pathogens, comprising members of four genera, that cause the intestinal epithelial microvilli to be replaced with raised clusters of filamentous actin that conform to the surface of attached bacteria. We have cloned a 35.4 kb 'pathogenicity island' from the prototype AE bacterium, enteropathogenic Escherichia coli, con...
the present study was conducted to investigate the role of summary in teaching grammar process on pre-university students. to this end, 48 male pre-university students in semnan were participants. they were math class that we called experimental group and science class as control group. in order to make sure there was no significant difference in proficiency level of two groups. a pre-test wa...
هدف از انجام این تحقیق ارزیابی اثر تکرارهای مکرر hcg بر روی ویژگیهای جسم زرد و فولیکولهای موجود بر سطح تخمدان و غلظت پروژسترون میش های سنجابی سوپراووله شده با ecg می باشد. تعداد 40 راس میش سنجابی بوسیله اسفنج آغشته به پروژسترون به مدت 12 روز جهت همزمان سازی فحلی مورد درمان قرار گرفتند . سوپراوولاسیون در این دامها بوسیله ecg، 2روز قبل از خروج اسفنج القاء شد. در روز خروج اسفنج (روز صفر) میش ها بص...
Marek's disease virus (MDV) and reticuloendotheliosis virus (REV) cause Marek's disease (MD) and reticuloendotheliosis (RE), respectively. Co-infection with MDV and REV is common in chickens, causing serious losses to the poultry industry. However, experimental studies of such co-infection are lacking. In this study, Chinese field strains of MDV (ZW/15) and REV (JLR1501) were used as challenge ...
Hemin is an important nutrient for Porphyromonas gingivalis growth and pathogenicity. We examined the gene expression profile of P. gingivalis, including genes involved in its pathogenicity, at various growth stages under hemin-standard and limited conditions by using a custom-made microarray. The transcription of many genes decreased after late-log and mid-log phases under hemin-standard and l...
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