BACKGROUND Pediatric cancer survivors are at risk for multiple late effects including second malignancies, some a direct consequence of genetic susceptibility. Appropriate surveillance and management for the survivor and at-risk family members can often be established if the genetic predisposition is recognized and/or diagnosed. Numerous published guidelines outline which adult cancer patients ...

Adolescent survivors of pediatric brain tumor (PBT) are a sparsely studied subset childhood cancer survivors. Sustaining PBT may complicate the development executive functions (EFs), which play vital role in long-term psychosocial adjustment. In this study, 48 adolescent and their parents completed questionnaires assessing EF, psychological symptoms, fatigue, adaptive functioning, 26 underwent ...

BACKGROUND The population of long-term survivors of childhood brain tumors (BTs) is growing. The aim of our study was to evaluate late-appearing morbidity in BT survivors. METHODS Patients diagnosed with a BT at the age of 0-15 years between 1970 and 2004, and surviving at least 5 years, were identified from the Finnish Cancer Registry (n = 740). Their late new morbidity ≥ 5 years after cance...

Recent progress in the treatment for pediatric malignancies using a combination of surgery, chemotherapy, and radiotherapy has improved survival. However, late toxicities of radiotherapy are a concern in long-term survivors. A recent study suggested reduced secondary cancer and other late toxicities after proton beam therapy (PBT) due to dosimetric advantages. In this study, we evaluated the sa...

PURPOSE/OBJECTIVES To describe the meaning of being cared for and comforted by pediatric oncology nurses among a sample of childhood cancer survivors. RESEARCH APPROACH A hermeneutic analysis was conducted to describe the meaning of the phenomenon. SETTING An oncology treatment center in the northeastern United States. PARTICIPANTS 11 childhood cancer survivors. METHODOLOGIC APPROACH Fo...

OBJECTIVE To compare the risk of posttraumatic stress (PTS) symptoms and the mediating effect of perceived future threat on the risk of PTS symptoms among survivors of pediatric cancer and children who had a parent die. METHODS Seventy-eight children (39 survivors of cancer, 39 bereaved) completed self-report measures of PTS symptoms, depression, anxiety, and perceived risk of future threat f...

Pediatric Neurocritical Care diagnoses account for a large proportion of intensive care admissions. Critical care survivors suffer high rates of long-term morbidity, including physical disability, cognitive impairment, and psychosocial dysfunction. To address these morbidities in Pediatric Neurocritical Care survivors, collaboration between Pediatric Neurology and Pediatric Critical Care create...

OBJECTIVE To analyze traits of metabolic syndrome (MetS) in medulloblastoma survivors. SUBJECTS AND METHODS Sixteen childhood medulloblastoma survivors aged 18.0 (4.4) years, with history of craniospinal radiation therapy (RT) were compared with nine control subjects matched by age, gender, and body mass index, according to fat distribution, metabolic and cardiovascular variables. RESULTS M...

BACKGROUND Pneumonia is the leading cause of death in children. Few studies have explored the predictive value of copeptin in pediatric pneumonia. AIM This study aimed to assess the role of copeptin as a marker of severity of community-acquired pneumonia (CAP). METHODS This prospective case-control study was carried out at Minia University Children's Hospital in Minia (Egypt) from January t...