Background: Dysregulation of LncRNA antisense non-coding RNA in the INK4 locus (ANRIL) expression is implicated in pathogenesis and disease progression of a variety of cancer types. However, the expression level of ANRIL in pediatric patients with B-cell precursor acute lymphoblastic leukemia (BCP-ALL) has not been elucidated, yet. The present study is an attempt to evaluate the expression leve...

Inflammation plays a critical role in the progression of cancer in children. On the other hand, children with cancer experience abnormal activation of the inflammatory system. Moreover, it is known that these patients have a predisposition to depression. According to studies, moderate to severe depression was observed in about 63% of children with cancer and acute illness. Therefore, identifyin...

OBJECTIVES Survival for hematopoietic stem cell transplant patients requiring pediatric intensive care unit admission may be improving. This study was conducted to review outcomes for patients undergoing hematopoietic stem cell transplantation requiring admission to our pediatric intensive care unit and to identify variables impacting survival. DESIGN Retrospective database review. SETTING ...

Visceral leishmaniasis is endemic in most parts of Kerman province. During eleven years, 40 patients in pediatric age group were admitted to the pediatric ward at the university hospital No.1 in Kerman. Fever and hepatosplenomegaly were the two most common clinical findings while leukopenia, thrombocytopenia and anemia were the most common laboratory findings, in 60℅ of cases the diagnosis was ...

Abstract Despite significant evidence that the expression of several microRNA’s (miRNA) impacts on disease activity in patients with ulcerative colitis (UC), it remains unknown if more severe phenotype seen pediatric-onset UC can be explained by altered miRNA expression. In this study, we aimed to assess relationship between expression, age, and severity pediatric adult UC. Using RT-qPCR, analy...

This study aims to synthesize evidence/literature on the use of information system technology in applying active and passive distraction techniques reduce pain scores pediatric patients. The research method used this is a literature review. results based search for articles using PICOT framework database Google Scholar were limited range last ten years, 2010-2020, which obtained five journals. ...

PURPOSE To assess the reliability of percutaneous nephrolithotomy (PNL) in pediatric patients by comparing complications between pediatric patients and adults by use of the modified Clavien grading system. MATERIALS AND METHODS The data of 74 pediatric (0 to 16 years) and 535 adult (17 years and older) patients who underwent PNL owing to kidney stone disease between January 2005 and December ...

Pediatric HIV patients often suffer with neurodevelopmental delay and subsequently cognitive impairment. While tissue injury in cortical and subcortical regions in the brain of adult HIV patients has been well reported there is sparse knowledge about these changes in perinatally HIV infected pediatric patients. We analyzed cortical thickness, subcortical volume, structural connectivity, and neu...

Introduction: Logbooks show whether medical students have been exposed to a particular disease and whether they are able to perform particular practices or not. To evaluate the training status of the medical students in the pediatric ward of Shiraz University of Medical Sciences, the data about the students’ knowledge of different diseases in different parts of the pediatric ward in 2011 was co...