Pemphigoid gestationis or herpes gestationis is a subepidermal blistering disease that occurs in women in the second or third trimesters of pregnancy or even during puerperium. It is a rare skin disease whose incidence has been estimated at around 1 case in every 40 000 to 60 000 pregnancies. It is more common in patients with HLA DR3 and DR4 haplotypes. Although most cases respond well to oral...

Lichen planus pemphigoides (LPP) is a rare condition characterized by tense blisters that arise on lesions of lichen planus (LP) and on unaffected skin. We present the case of a 25-year-old pregnant woman at 12 weeks' gestation who developed an acute bullous eruption after 5 months of worsening LP. Similarities to pemphigoid gestationis (PG) included lesions around the periumbilical area and mu...

Certain dermatoses are specifically seen in pregnancy or postpartum period. It is therefore important for the clinicians to recognize and treat these cutaneous disorders to minimize maternal and fetal morbidity. The commonest pregnancy related dermatoses was polymorphic eruption of pregnancy seen in 22% patients, prurigo of pregnancy was seen in 7% patients, pemphigoid gestationis was seen in 3...

Bullous Diseases Unit at the 2nd Department of Dermatology and Venereology, Aristotle University of Thessaloniki was founded with the aim to provide the optimal diagnostic approach and treatment of patients with autoimmune bullous diseases (AΙBD). We processed all AIBD files of patients diagnosed from 2011 to 2014 in order to record all epidemiological data and therapeutic manipulations during ...

Pemphigoid gestationis (PG) is an autoimmune pregnancy dermatosis that rarely affects the oral mucosa. PG is mediated by an autoimmune response to BP180, a 180-kDa trans-membrane hemidesmosomal glycoprotein. Diagnosis of PG requires careful consideration of clinical signs and symptoms in combination with histopathologic and immunophenotypic analyses. Systemic corticosteroid administration is cu...

Pemphigoid gestationis (PG) is a rare auto-immune bullous disease of pregnancy that is characterized by linear deposition of C3 along the basal membrane zone of lesional, perilesional and uninvolved skin when examined by direct immunofluorescence. Circulating antibodies of IgGl class are also present. The aberrant expression of MHC class II molecules in the placenta appears to be important in t...