Mesenchymal stem cell (MSC) therapy is an emerging field of regenerative medicine; however, it is often unclear how these cells mediate repair. Here, we investigated the use of MSCs in the treatment of intestinal disease and modeled abnormal repair by creating focal wounds in the colonic mucosa of prostaglandin-deficient mice. These wounds developed into ulcers that infiltrated the outer intest...

OBJECTIVES To report a case series of thoracic bite trauma in dogs and cats and to evaluate risk factors for mortality. METHODS A retrospective study concerning thoracic bite wounds in dogs and cats was performed. Lesions were categorized by depth of penetration: no wound, superficial, deep or penetrating. Thoracic radiographic reports were reviewed. Lesion management was classified as non-su...

Current Opinion in Critical Care 2010, 16:609–617 Purpose of review Patients with penetrating abdominal trauma are at risk of harboring life-threatening injuries. Many patients are in need of emergent operative intervention. However, there are clearly patients who can be safely managed nonoperatively. This review evaluates the literature to identify management guidelines for patients with penet...

Introduction: Penetrating cardiac injuries generally occur secondary to gunshot or stab wounds and have a high mortality rate. They are rare and often fatal in children. When a foreign object penetrates the myocardium, it is dangerous to remove it, suddenly, and should be removed gradually to prevent excessive bleeding. Case report: We report a case of an unusual penetrating cardiac injury in a...

Penetrating wounds of the aorta are not necessarily fatal. A successfully managed patient with a stab wound of the ascending aorta is reported, and some problems of management associated with such injuries are discussed.

BACKGROUND The purpose of this study was to describe pelvic fractures and their associated injuries in service members who either died of wounds or were killed in action during Operation Iraqi Freedom and Operation Enduring Freedom and define any differences in associated injuries between penetrating versus blunt injury to the pelvis. METHODS A review of all service members who sustained a pe...

UNLABELLED The putative antinociceptive properties of a commercially available polymeric membrane dressing were tested by using a hind limb penetrating stab wound model in which secondary hyperalgesia could be evaluated from the hind paw. We examined the responses to mechanical and thermal stimuli applied to the hind paw remote to 2 small penetrating stab wounds of the calf. Application of the ...

A series of 100 penetrating wounds of the abdomen and thorax is reviewed. Eighty-three were due to stab-wounds. The recent increase in incidence is confirmed and the distribution throughout the day and months of the year is given. The results and methods of treatment of thirtysix abdominal, ten thoraco-abdominal and thirtyseven thoracic wounds are given and described. An operative approach to a...