Elastosis perforans serpiginosa (EPS) is a rare disorder classified as a primary perforating dermatosis. That group of diseases also includes reactive perforating col-lagenosis, perforating folliculitis or Kyrle disease. In EPS, protrusions of altered elastic fibers and other connective tissue material through the papillary layer and epidermis (called transepithelial elimination) clinically man...

Background Acquired perforating dermatosis (APD) is a rare skin condition characterized by degenerated materials eliminated from the dermis. Several retrospective studies on APD have been reported; however, few data are available Chinese and their features dermoscopy reflective confocal microscope (RCM) assays. Objective The aim of this study was to retrospectively evaluate clinical histopathol...

A 14-year-old Indian boy presented with gradually progressive pruritic lesions over both lower legs for 6 months. On examination, we found multiple, hyperpigmented, keratotic papules and plaques over the anterior, posterior, and lateral sides of distal parts of both lower extremities [Figure 1a and b]. The mucosae, nail, hair, and systemic examinations were noncontributory. There was no history...

restoring normal iron levels; this diagnosis had to be considered in our patient as the first biopsies were compatible with this skin disorder. From a clinical point of view, the differential diagnosis must include other skin conditions that have been described in association with bariatric surgery, such as dermatosisarthritis syndrome, neutrophilic dermatosis attributed to the formation of cir...

Elastosis perforans serpiginosa (EPS) is a rare reactive perforating dermatosis that is characterized by the transepidermal elimination of abnormal elastic fibers. Penicillamine, which is one of the clear triggers for EPS, is a heavy metal chelator that is primarily used for disorders such as cystinuria and Wilson's disease. It may cause alterations in the dermal elastic tissue such as pseudo-p...

CONTEXT There are a variety of dermatological diseases that are more commonly seen in patients with chronic kidney disease (CKD) and renal transplants than the general population. EVIDENCE ACQUISITIONS Directory of Open Access Journals (DOAJ), Google Scholar, Pubmed (NLM), LISTA (EBSCO) and Web of Science has been searched. RESULTS Some cutaneous diseases are clearly unique to this populati...

Acquired perforating dermatosis (APD) is a skin disorder occurring in the patients with chronic renal failure (CRF), diabetes mellitus (DM) or both. The purpose of this study was to clarify the clinical and histopathological features of APD, and evaluate role of scratching in the pathogenesis of APD. Twelve patients with APD associated with CRF and DM were enrolled in the study. In six patients...