Introduction: It is recommended that the physician apply at least a semi-quantitative segmental scoring system in myocardial perfusion SPECT.  We aimed to assess the agreement between automated semi-quantitative analysis using QPS (quantitative Perfusion SPECT) software and visual approach for calculation of summed stress  score (SSS), summed rest score (SRS) and summed difference score (SDS). ...

Background Quantitative cardiovascular magnetic resonance (CMR) myocardial perfusion imaging has the potential to evolve into a routine clinical method allowing for the assessment of myocardial blood flow (MBF). Multiple quantification pathways are available based on different algorithms. These algorithms involve complex modeling and quantitative results may not necessarily be the same. At pres...

Introduction While water was initially considered as a freely diffusible tracer in arterial spin labeling (ASL) perfusion MRI, emerging evidence suggested a limited degree of water exchange between the vascular (capillary) and tissue compartments (1, 2). Quantification of water extraction fraction and permeability is important for accurate perfusion quantification in ASL methods, and may provid...

Noninvasive quantification of myocardial perfusion in absolute terms has gained increasing interest recently. Although the technique has been available for 2 decades, only lately quantification has become feasible in clinical routine. This has been facilitated by wider clinical use of positron emission tomography (PET) in cardiac patients and the technical development of imaging cameras and sof...

Background Recent developments in cardiovascular magnetic resonance (CMR) perfusion have made it possible to rapidly acquire multiple slices continuously without the need for any ECG-triggering. Promising results have been shown for visual assessment and quantification of perfusion using self-gated techniques [1-3]. This work compares the repeatability of a free breathing ungated acquisition us...

Recently it has been shown that regional lung perfusion can be assessed using time-resolved contrast-enhanced magnetic resonance (MR) imaging. Quantification of the perfusion images has been attempted, based on definition of small regions of interest (ROIs). Use of complete lung segmentations instead of ROIs could possibly increase quantification accuracy. Due to the low signal-to-noise ratio, ...

Background Accurate assessment of relative reductions in regional myocardial blood flow (MBF) is clinically important in identifying haemodynamically significant coronary artery disease. First-pass perfusion magnetic resonance imaging allows for a non-invasive and radiation free quantification of MBF. One of the advantages of MR perfusion over nuclear medicine techniques is better spatial resol...

Perfusion Myocardial perfusion SPECT (MPS) studies are frequently performed serially to monitor progression of coronary artery disease. MPS also plays an important role in evaluating therapies for coronary artery disease (1). Sensitive methods for detection and estimation of changes in myocardial perfusion over time could improve confidence in using MPS for these applications (2–5). The use of ...

BACKGROUND Microvascular ischemia is one of the hallmarks of hypertrophic cardiomyopathy (HCM) and has been associated with poor outcome. However, myocardial fibrosis, seen on cardiovascular magnetic resonance (CMR) as late gadolinium enhancement (LGE), can be responsible for rest perfusion defects in up to 30% of patients with HCM, potentially leading to an overestimation of the ischemic burde...