Perianal fistula is a common disease affecting the general population but development of mucinous adenocarcinoma (MA) in chronic perianal rare entity. Due to nature disease, there are no established guidelines regarding diagnosis and management condition. The aim this article report case MA region that we managed surgically with an extra levator abdominoperineal resection flap reconstruction.

BACKGROUND Crohn's disease (CD) is a chronic idiopathic inflammatory bowel disease involving the whole gastrointestinal tract. TNFSF15 has been proved as a susceptibility gene for CD, but there are few reports about the association between TNFSF15 single nucleotide polymorphisms (SNPs) and the clinical course of CD. AIM To investigate the association between TNFSF15 genotypes and the clinical...

Up to 20% of patients with Crohn's disease (CD) may have perianal fistula disease, which is frequently associated with perianal collections [1]. Classically, surgery has played an important role, by the placement of drains or setons creation of ostomies, and in severe cases, even proctectomy [2]. However, in recent years, medical treatment with or without the temporary placement of drains, has ...

In population-based studies, up to 50% of patients with Crohn's disease suffer from fistulas. Fistulas pose a considerable morbidity including permanent sphincter and perineal tissue destruction as well as professional and personal disabilities. Treatment options have progressed in recent years and fistula closure and fibrosis of the fistula track is achieved in some patients. Depending on seve...

OBJECTIVE To evaluate the effectiveness of endoanal ultrasound with hydrogen peroxide enhancement in the assessment of anal fistula (tract and internal opening), and to value the utility of this examination for anal or perianal suppuration when performed by a colorectal surgeon trained in this technique. PATIENTS Endoanal ultrasound was performed in 103 patients with anal or perianal suppurat...

Correction After the publication of this work [1] it was brought to the authors attention that Figure five (Figure 1 here) contained a duplication error in the PDF format, where it featured a perianal fistula instead of a rectovestibular fistula in females. The correct figure is given below: We regret any inconvenience that this inaccuracy may have caused. Figure 1 Rectovestibular fistula in fe...

Background and Aims: Perianal abscess is one of the most frequent proctological disorders and needs urgent treatment. Incision and drainage consists the gold standard therapy of this disorder. However, due to high rates of abscess recurrence, few surgeons favor primary fistula treatment at the time of abscess drainage to decrease the risk of recurrence. This clinical study was designed to compa...

MRI is a diagnostic imaging tool crucial for pelvic examination in perianal fistula cases. offers some advantages, especially showing the area of spesi and secondary dilatation. Both have high recurrence rate after surgery an important role determining surgical outcomes minimizing complications. This study aims to evaluate fistulas using T2 TSE SPIR (Turbo Spin Echo Spectral Presaturation with ...

OBJECTIVE Malignant transformation of fistulas has been observed, particularly in perianal fistulas in Crohn's disease (CD) patients. The prevalence of adenocarcinoma in enterocutaneous fistulas and non-CD-related fistulas, however, is unknown. We investigated adenocarcinoma originating from perianal and enterocutaneous fistulas in both CD patients and non-CD patients from nine large, mostly te...

Ulcerative colitis is a chronic inflammatory bowel disease of unknown etiopathogenesis and increasing incidence in recent years. Perianal complications of ulcerative colitis are rare and seem to be associated with higher extent of inflammation and a more severe course of the disease. The cases of two male patients with severe corticoid-dependent ulcerative colitis of protracted clinical course ...