UNLABELLED Periodontal health can be restored through assessment, diagnosis, treatment and management of periodontal osseous defects by the periodontist-dental hygienist team. BACKGROUND AND PURPOSE Treatment of periodontitis has evolved over time, with regenerative periodontal therapy at the forefront in cutting-edge periodontal care. While the techniques and materials available today are al...

Periodontitis is one of the most prevalent infectious diseases in human beings, characterized by irreversible destruction on tooth supporting tissues such as alveolar bone, Periodontal Ligaments (PDL) and cement. The pathogenesis involves a complex interaction between the host’s immune response to microbial colony localized in periodontal part, and modifying host factors, including smoking, gen...

Periodontal disease is categorized by the destruction of periodontal tissues. Over the years, there have been several clinical techniques and material options that been investigated for periodontal defect repair/regeneration. The development of improved biomaterials for periodontal tissue engineering has significantly improved the available treatment options and their clinical results. Bone rep...

periodontal regeneration is a main aspect in the treatment of teeth affected by periodontitis. periodontal regeneration in furcation areas is quite challenging, especially when it is in interproximal region. there are several techniques used alone or in combination considered to achieve periodontal regeneration, including the bone grafts or substitutes, guided tissue regeneration (gtr), root su...

Brain-derived neurotrophic factor (BDNF), for which bovine collagen-derived atelocollagen is used as a scaffold, enhances periodontal tissue regeneration. However, a scaffold that does not contain unknown ingredients is preferable. Since the synthesized high-molecular-weight (HMW)-hyaluronic acid (HA) is safe and inexpensive, we evaluated the efficacy of HMW-HA as a BDNF scaffold. CD44, a major...

The ultimate goal of periodontal treatment is not only the stabilization of periodontal disease but also regeneration of the periodontal tissues destroyed by severe periodontitis. The tissue engineering triad of stem cells, biological signals, and cell-seeded scaffold provides a biological template for tissue regeneration. Neural crest stem cells (NCSC) comprise a transient multipotent stem cel...

1.1 Regenerative periodontal therapy The goal of periodontal therapy is to improve periodontal health and thereby to satisfy the patient’s esthetic and functional needs or demands. To achieve this goal, most periodontal treatments aim to reduce probing depths and maintain or improve attachment levels and these parameters are used as surrogates of improved tooth retention. Conventional periodont...

The goal of periodontal therapy is to protect and maintain the patient’s natural dentition for his or her lifetime. More specifically, after periodontal regenerative surgery, the aim is to achieve complete wound healing and regeneration of the periodontal unit. A recent innovation in dentistry is the preparation and use of platelet-rich plasma (PRP), a concentrated suspension of the growth fact...

Periodontal disease is a major public health issue and the development of effective therapies to treat the disease and regenerate periodontal tissue is an important goal of today's medicine. Regeneration of periodontal tissue is perhaps one of the most complex process to occur in the body. Langer and colleagues proposed tissue engineering as a possible technique for regenerating the lost period...