BACKGROUND Concern that measles-mumps-rubella (MMR) vaccination might cause autism has led to a fall in vaccine coverage. We investigated whether MMR vaccination is associated with an increased risk of autism or other pervasive developmental disorders. METHODS We did a matched case-control study using the UK General Practice Research Database. Cases were people born in 1973 or later who had f...

Previous research on developmental dyscalculia (DD) suggested that deficits in the number line estimation task are related to a failure to represent number magnitude linearly. This conclusion was derived from the observation of logarithmically shaped estimation patterns. However, recent research questioned this idea of an isomorphic relationship between estimation patterns and number magnitude ...

Because mathematics is fundamentally symbolic—even totally symbolic at a higher level—the recent finding by Skagerlund and Träff (2014a) that fourth graders with developmental dyscalculia (DD) exhibit intact symbolic number processing seems curious. The importance of symbolism in mathematics is such that the finding seems contradictory with the notion of dyscalculia. Here I discuss three concer...

Developmental dyscalculia (DD) is thought to arise from difficulties in the ability to process numerical magnitudes. Most research relied on IQ-discrepancy based definitions of DD and only included individuals with normal IQ, yet little is known about the role of intelligence in the association between numerical magnitude processing and mathematical difficulties (MD). The present study examined...

Individuals with autism spectrum disorder (ASD) often have difficulty coordinated fine motor skills, but the degree of significantly varies from person to person. To elucidate cause this diversity, we monitored brain activity during movement tasks (tying bowknots) by near-infrared spectroscopy in 17 adults ASD and 18 typical development matched for age, gender, intelligence quotient (IQ). We al...