Botanicals are gaining importance in recent times as active ingredients for cosmetic formulations due to their dermal protective effect against the harmful substances from endogenous and exogenous sources. The probability of exposure of the skin to UV radiation and other environmental factors are more since it is present in the outer layer of body as the primary defense mechanism. The exposure ...

Colliod milium is a degenerative change, which is characterized clinically by development of multiple yellowish, translucent papules and nodules on the light exposed skin and histologically by the presence of colloid in the dermal papillae. This is a rare condition and has some variants. We report a case of colloid millium with nodular and plaque lesions on his ears. Our patient was a far...

BACKGROUND AND OBJECTIVES Many laser, light and energy emitting devices are utilized for skin rejuvenation. STUDY DESIGN/MATERIALS AND METHODS The clinical approach to multiple problems of photoaging are discussed and an algorithm for approach by problem is presented. RESULTS Clinical use of various modalities such as LED photomodulation, intense pulsed light, pulsed dye laser, KTP laser, r...

BACKGROUND Advances in nonablative skin rejuvenation technologies have sparked a renewed interest in the cosmetic treatment of aging skin. More options exist now than ever before to reverse cutaneous changes caused by long-term exposure to sunlight. Although Caucasian skin is more prone to ultraviolet light injury, ethnic skin (typically classified as types IV to VI) also exhibits characteristi...

Collagen tripeptide (CTP) is a functional food material with several biological effects such as improving dry skin and wound and bone fracture healing. This study focused on the anti-photoaging effects of CTP on a hairless mouse model. To evaluate the effects of CTP on UVB-induced skin wrinkle formation in vivo, the hairless mice were exposed to UVB radiation with oral administration of CTP for...

BACKGROUND Intake of monounsaturated fatty acids has been reported to reduce oxidative stress, insulin resistance and related inflammatory processes and may thus protect from skin photoaging. The objective of this study was to investigate the association between the risk of photoaging, monounsaturated fatty acids intake and the sources of monounsaturated fatty acids. METHODOLOGY/PRINCIPAL FIN...

UV exposure is associated with oxidative stress and is the primary factor in skin photoaging. UV-induced reactive oxygen species (ROS) cause the up-regulation of metalloproteinase (MMPs) and the degradation of dermal collagen and elastic fibers. Garlic and its components have been reported to exert antioxidative effects. The present study investigated the protective effect of garlic on UV-induc...

Long-term sun exposure markedly accelerates the skin changes of chronological aging, leading to deterioration function and appearance in a process termed Photoaging. The molecular mechanisms underlying photoaging remain incompletely defined, due largely limitations ex vivo studies. To interrogate this phenomenon vivo, we performed single-cell RNA-seq sun-protected sun-exposed from four ∼20-year...

BACKGROUND It has been reported that intense pulsed light is efficacious for rejuvenation of photoaged skin, specifically the improvement of appearance of telangiectases and solar lentigines. OBJECTIVE The objective was to define the treatment variables for photodamaged facial skin using a newer intense pulsed light system. METHODS Twenty-three female subjects received three treatments usin...

BACKGROUND Intense pulsed light has been used in the treatment of photoaging without a full understanding of its mechanism of action. OBJECTIVE To study the effect of intense pulsed light on photoaging and on the skin immune response by means of a clinical and histopathological study, evaluating Langerhans cells (CD1), expression of intercellular adhesion molecule, of CD4 and CD8 lymphocytes ...