In spite of considerable efforts to identify effective treatments for urolithiasis, this is a goal yet to be achieved. This review summarizes experimental and clinical data evaluating the effect of the plant Phyllanthus niruri, a plant with worldwide distribution, as a potential agent to prevent and/or to treat urolithiasis The review is based on data from the literature and on the results obta...

The genus Phyllanthus consists of more than 1000 species, of which many are used as traditional medicines. The plant extracts have been used since ancient times, for treating hypertension, diabetes, hepatic, urinary, and sexual disorders, and other common ailments. Modern day scientific investigations have now confirmed pharmacognostic properties of Phyllanthus herbs. The phytochemicals attribu...

to treat a variety of malignacies, such as leukemias, breast and ovarian cancer, and Hodgkin and non-Hodgkin lymphoma. The major limitation of clinical use is the development of cardiotoxicity. The adverse effects are dose dependent and can vary from transient electrocardiographic abnormalities to cardiomyopathy and heart failure. Recent studies have suggested that the mechanism of DOX-induced ...

The objective of the present study was to evaluate the protective effect of Phyllanthus emblica against clastogenicity induced by lead nitrate on the incidence of sperm head abnormalities in the germ cells of mice. At higher concentration of lead, a significant increase in the percentage of sperm head abnormalities was noted but when animals primed with Phyllanthus fruit extract (PFE), a reduct...

Anti inflammatory potential of aerial parts of Phyllanthus longiflorus was investigated in the present study using acute and chronic inflammatory models. Carrageenan, dextran and formalin were used as an edematogenic agent to induce hind paw edema in rats and the mean increase in paw volume were measured using plethysmometer. Results showed that methanol extract of Phyllanthus longiflorus at th...

Introduction: The perennial herb Phyllanthus niruri, belonging to the family Euphorbiaceae is commonly known as Bhuiavala in Marathi and possess antibacterial, analgesic, antipyretic, anti-hepatotoxic, antifungal and anthelmintic activity. Objective: The present study was carried out to validate the in vitro anthelmintic activity of hot aqueous whole plant extract of Phyllanthus niruri against ...

A new species, Phyllanthus mutisianus, is described on the basis of a collection from Colombia made by the expedition of Jose Mutis. It is distinguishable from all other neotropical species of Phyllanthus by virtue of the distinctive leaf venation and very long fruiting pedicels. The type specimen lacks mature flowers, but the vegetative morphology, inflorescence, and fruiting structures sugges...

Herbs have always formed an integral part of human health and are used in the treatment of several human diseases. One of such species which have wide patronage of use is Phyllanthus amarus. This herb is in traditional medicine for more than 3,000 years. The plant has also served as lead for several experimental investigations that explored its phytochemical constituents and pharmacological use...

HIV is the etiological agent of AIDS that has created major health care problem throughout the world. The aim of the present study is to evaluate the cytotoxic effects and anti-HIV activity of Phyllanthus niruri whole plant extracts. Hexane, chloroform, ethyl acetate, acetone and methanol solvents were used to prepare the extracts by sequential maceration method. RetroSys HIV-1 RT (Innovagen, S...