Neonatal jaundice can be a major health threat to the newborn. The present study compared the effects of Liv.52 to that of phenobarbitone with a third group serving as control, in a total of 260 newborn babies. It was found that Liv.52 pretreatment has no deleterious effect on development of icterus. Continued treatment with Liv.52 led to early disappearance of icterus. It was also safe, withou...

In many developing countries, jaundice is the common symptom of hepatic diseases which are a major cause of mortality. The use of natural product-based therapies is very popular for such hepatic disorders. A great number of medicinal plants have been utilized for this purpose and some facilitated the discovery of active compounds which helped the development of new synthetic drugs against jaund...

BACKGROUND An exchange transfusion involves replacing patient's blood with donor blood in order to remove abnormal blood components and circulating toxins while maintaining adequate circulating blood volume. OBJECTIVE To observe the incidence, causes of jaundice requiring Exchange and any adverse event of exchange transfusion in newborns with unconjugated hyperbilirubinemia. METHOD Prospect...

Breast-fed infants have higher bilirubin level than formula-fed infants which is of undetermined etiology. The cholestatic effect of cytokines (e.g. IL-1beta, IL-6) is believed to result from the repression of genes that normally mediated the hepatic uptake, metabolism, and biliary excretion of bile salts and bilirubin. The present study aimed to assess the level of interleukin 1beta (IL1beta) ...

Prediction of diseases would help physicians to make informal decision regarding the type of treatment. Jaundice is the most common condition that requires medical attention in newborn babies. Although most newborns develop some degree of jaundice, a high level bilirubin puts a newborn at risk of bilirubin encephalopathy and kernicterus, which are rare but still occur in Egypt. This paper prese...

background: jaundice is a common condition among neonates. prolonged unconjugated hyperbilirubinemia occurs when jaundice persists beyond two weeks in term neonates and three weeks in preterm neonates. this study aimed to determine the etiologies of prolonged unconjugated hyperbilirubinemia in infants admitted to the neonatal ward of besat hospital in hamadan, iran. methods: this study was cond...

Background: Now hemoperfusion has not been used for the treatment of severe neonatal jaundice, and bilirubin adsorbent with high adsorption and safety should be the prerequisite for the use. Objectives: To investigate the adsorption of six kinds of current adult/industrial bilirubin adsorbents from severe neonatal jaundice plasma, then screen the best one with highest adsorption for further eva...

This publication summarizes the scientific adventure with Professor Selye, and focuses on the specific effect of rare metal salts on reticuloendothelial functions. Rare earth metal ions markedly affect the functions of cells involved in inflammatory and immunological phenomena. The Kupffer cell blockade induced by GdCl3 is a generally accepted method for investigation of the physiological and p...

Breast milk jaundice is a kind of caused by breastfeeding in new-borns. It occurs within the first week life as result an aberrant accumulation bilirubin, resulting jaundice, and yellowish staining neonate's skin. Objectives study were to depict breastmilk its etiology, review pathophysiology discuss medical nursing management jaundice.

background: clofibrate is an effective anti lipid agent that induces glucuronyltransferase could increase bilirubin conjugation. the aim of this study was to evaluate effect of clofibrate on neonatal physiologic jaundice. methods: randomized clinical trial sampling method used and 60 healthy term neonates which were admitted in imam reza hospital of kermanshah-iran because of indirect hyperbili...