A 23-year-old previously healthy Dutch woman developed an erythematous, non-itching rash in a handprint pattern at the lateral side of her left thigh on the fourth day of a beach holiday in Bali. Apart from her stay on the beach and an enjoyable nightlife, her further exposure and travel history was unremarkable. In the following 24 hours, the rash became extremely painful with development of b...

Phototoxic and photoallergic reactions represent skin reactions to the sun, in the presence of photoactive chemicals applied on the skin or taken systemically. They have a highly polymorphic clinical presentation – photo contact urticaria, eczema on sun-exposed areas sometimes with erythema multiforme, exaggerated sunburn, linear phytophotodermatitis, pseudoporphyria, photoonycholysis, dyschrom...

environmental triggers. It is inherited as an autosomal trait and may be triggered by stimuli including sunlight and artificial UV light, viral infections, immunosuppressive conditions (hematologic malignancies, organ transplant, or autoimmune disease), and immunosuppressant therapies. The role of immunosuppressant therapy is supported by the observation in at least 1 case report of remission o...

Abstract Introduction The Giant Hogweed (Heracleum mantegazzianum) is a rare cause for chemical burns in humans and animals acquiring growing recognition mainstream media as relevant public health concern. Injuries attributed to this plant range from innocuous superficial irritation full-thickness burns. A vast majority of cases will resolve with conservative measures effective first aid, but t...

It is usually present at birth in the two thirds of patients who have ocular involvement.It is more common in females with 5% being bilateral.4 It was first described by Ota in 1939. It can be unilateral or bilateral. Exact etiology and pathology of NOO is not known. Unconfirmed hypothesis is that it represents melanocytes that have not migrated completely from the neural crest to the epidermis...

Abstract A male infant presented to his general practitioner for a routine 6-week check. His parents reported the presence of tan–brown lesions since birth. The marks were uniform in colour, present on trunk, scalp and face, not overlying bony prominences. There was concern that these represented bruising as manifestation nonaccidental injury (NAI), urgent paediatric review arranged. He admitte...