Pigmentary demarcation lines are common, especially in individuals with darker skin types. Type B pigmentary demarcation lines (Futcher lines) involve the posterior lower extremities and can be associated with pregnancy, often with spontaneous resolution after delivery. The pathogenesis of pigmentary demarcation lines remains unknown; however, neurogenic inflammation and/or mosaicism are though...

Unilateral sensorineural hearing loss (USNHL)/single-side deafness (SSD) is a frequently encountered disability in children. The etiology of a substantial portion of USNHL/SSD still remains unknown, and genetic causes have not been clearly elucidated. In this study, the authors evaluated the heritability of USNHL/SSD.The authors sequentially recruited 50 unrelated children with SSD. For an etio...

In this article, we are collectively presenting case reports of 15 patients who developed pigmentary changes of the skin and mucus membrane during the course of chloroquine therapy for connective tissue disorders. These female patients developed hyper pigmentation of the skin, largely on the exposed parts of the body. The pigmentary changes varied from brownish/ grayish/ bluish-black in color, ...