The size dependent features of colloids at the nanometer scale have been issues of increasingly intensive research. In order to be able to correctly relate characteristics to certain size-populations, accurate and reliable particle sizing by dynamic light scattering (DLS) is a main prerequisite. So far, the complexity of the systems due to the presence of surfactants, proteins, and so forth in ...

In the present study solid dispersions of the antifungal drug Ketoconazole were prepared with Pluronic F-127 and PVP K-30 with an intention to improve its dissolution properties. Investigations of the properties of the dispersions were performed using release studies, Differential scanning calorimetery (DSC), X-ray powder diffraction (XRD) and Fourier transform infrared (FTIR). The results obta...

In article number 2004452, Dermot F. Brougham and co-workers demonstrate 3D printable responsive magnetic hydrogels composed of iron oxide nanoflowers Pluronic polymers that encode spatiotemporally controlled temperature increase dye release on alternating field irradiation.

BACKGROUND Surfactants may reduce the adhesion force holding bubbles to the vessel wall in gas embolism. The authors measured bubble adhesion force using excised microvessels. They assessed endothelial damage by measuring vessel reactivity and with microscopy. METHODS Microbubbles injected into arterioles resided for 5, 10, or 30 min, with intact or damaged endothelium. Perfusion was with rat...

We describe a simple, efficient, gentle and inexpensive technique for the introduction of normally impermeant macromolecules into the cytosol of living mammalian cells growing in suspension or attached to the culturing substratum. Loading is achieved by the production of transient, survivable plasma membrane disruptions as cells are passed back and forth through a standard syringe needle or sim...

The objective of this study was to prepare PLGA nanoparticles of Carvedilol that will improve the bioavailability of Carvedilol and sustain the release to reduce the initial hypotensive peak and to prolong the antihypertensive effect of the drug. Carvedilol encapsulated by Nanoprecipitation method using PLGA and Pluronic F-68.Prepared nanoparticles were examined for physicochemical characterist...

6-O-(4,4,5,5,6,6,7,7,7-Nonafluoro-2-hydroxyheptyl)-, 6-O-(4,4,5,5,6,6,7,7,8,8,9,9,9-tridecafluoro-2-hydroxynonyl)-, and 6-O-(4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,11-heptadecafluoro-2-hydroxyundecyl)-d-galactopyranose (9, 10, and 11, resp.) were prepared by a two-step synthesis including the reaction of 1,2:3,4-di-O-isopropylidene-alpha-d-galactopyranose with 2-[(perfluoroalkyl)methyl]oxiranes un...

Wave mixed single-use bioreactors (also called rocking bioreactors) are a group of devices in which mixing is caused by characteristic wave-like movement liquid inside pillow-shaped bag mounted on continuously oscillating platform. This study aimed to investigate the influence phase viscosity and presence an antifoaming agent mass transfer 2 liter used ReadyToProcess WAVE 25 bioreactor system. ...

This work reports on the new chemical dosimeters for UV radiation dose measurements coral reefs and in seawater. The proposed can measure actual of radiation, which consists 95% UVA 5% UVB unlike currently-used radiometers marine ocean waters that separately. are composed water, poly(ethylene oxide)-block-poly(propylene oxide)-block-poly(ethylene oxide) (Pluronic F-127) as a gel matrix, 2,3,5-t...

The aging mechanisms of perfluorocarbon emulsions were investigated using image analysis. Oil-in-water emulsions of two perfluorocarbons, n-perfluorohexane and perfluorodecalin, were prepared with three emulsifiers, Lecithin, Span 20, and Pluronic F-68. The effect of the temperature and the replacement of water by an aqueous phase consisting of a microbial culture medium were also studied. The ...