the aim of the research work was to chemically modify guar gum(gg) as a ph sensitive co-polymer and formulating intestinal targeting eso nanoparticles (nps) using the synthesized co-polymer. poly acrylamide-grafted-guar gum (paam-g-gg) co-polymer was synthesized by free radical polymerization. chemical modification of paam-g-gg by alkaline hydrolysis results in formation of a ph-sensitive co-po...

objective(s): the quantitative calculation of release data is more facil when mathematics come to help. mathematically modeling could aid optimizing and amending the delivery systems design. aim of this study is to find out the isoniazid release kinetic. methods: in this work degradable temperature sensitive dextran-hydroxy ethyl methacrylate- poly-n-isopropyl acryl amide (dex-hema-pnipaam) nan...

Objective(s): The quantitative calculation of release data is more facil when mathematics come to help. mathematically modeling could aid optimizing and amending the delivery systems design. Aim of this study is to find out the isoniazid release kinetic. Methods: In this work degradable temperature sensitive dextran-hydroxy ethyl me...

The aim of the research work was to chemically modify guar gum(GG) as a pH sensitive co-polymer and formulating intestinal targeting ESO nanoparticles (NPs) using the synthesized co-polymer. Poly acrylamide-grafted-guar gum (PAAm-g-GG) co-polymer was synthesized by free radical polymerization. Chemical modification of PAAm-g-GG by alkaline hydrolysis results in formation of a pH-sensitive co-po...

A new series of N-{4-(6-Chloro-5-nitro-1-[2'--(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-1Hbenzoimidazol-2yl-}-phenyl)-3-(substituted-phenyl)-acryl amide derivatives [1-8] has been synthesized and subjected to evaluate their antihypertensive activity. All the synthesized compounds of the series displayed, remarkable activity in comparison to standard drug(losratan ). Many Schiff bases were prepare...

Protein identification in polyacrylamide gel electrophoresis (PAGE) requires post-electrophoretic steps like fixing, staining and destaining of the gel, which are time-consuming and cumbersome. We have developed a method for direct visualization of protein bands in PAGE using tetrakis(4-sulfonato phenyl)porphyrin (TPPS) as a dye without the need for any post electrophoretic steps, where separat...

Two new samples of poly(amide-imide)/nanocomposites containing bicyclo segment and dibenzalaceton moiety in the main chain were synthesized by a solution intercalation technique. Poly(amide-imide) (PAI) 8 as a source of polymer matrix was synthesized by the direct polycondensation reaction of N,N´-bis(4-carboxyphenyl)bicyclo[2,2,2]oct-7-ene-2,3,5,6-tetracarboxylic diimide 3 with 2,6-bis(4-amino...

Five new aromatic poly(amide-imide)s (5a-e) were synthesized by direct polycondensationreaction of N-(4-carboxy phenyl) trimellitimide (3) with five aromatic diamines (4a-e) by usingtriphenyl phosphite in N-methyl-2-pyrrolidone (NMP) and pyridine at solution containingdissolved CaCl2. All of the polymers were obtained in quantitative yields with inherentviscosities between 0.29-0.40 dL/g. The r...

Two new samples of poly(amide-imide)/nanocomposites containing bicyclo segment and dibenzalaceton moiety in the main chain were synthesized by a solution intercalation technique. Poly(amide-imide) (PAI) 8 as a source of polymer matrix was synthesized by the direct polycondensation reaction of N,N´-bis(4-carboxyphenyl)bicyclo[2,2,2]oct-7-ene-2,3,5,6-tetracarboxylic diimide 3 with 2,6-bis(4-amino...

Poly(ester amide)s are an emerging group of biodegradable polymers that may cover both commodity and speciality applications. These polymers have ester and amide groups on their chemical structure which are of a degradable character and provide good thermal and mechanical properties. In this sense, the strong hydrogen-bonding interactions between amide groups may counter some typical weaknesses...