This work investigated the formation of acid milk gel at different length scales with and without addition iota -carrageenan (IC) (0.5% w/w) during incubation 30 °C, using bulk rheology syringe compression test macroscopic level, passive particle tracking (particle diameter 0.3 ?m 1.0 ?m) microscopic level pulsed field gradient (PFG)-NMR poly(ethylene oxide) (PEO) molecular level. IC induced ea...

In this study, we select naproxen (NAP) as a reference drug and electrospun poly (ɛ-caprolactone) (PCL) nanofibers as a fibrous matrix for our drug-delivery system. NAP was complexed with beta-cyclodextrin (βCD) to form inclusion complex (NAP-βCD-IC) and then NAP-βCD-IC was incorporated into PCL nanofibers via electrospinning. The incorporation of NAP without CD-IC into electrospun PCL was also...

It is known that mammalian spermatogenesis is a synchronous process of cellular differentiation during which morphological changes occur, concomitantly with alterations in the complement of constituent proteins, that reflect differences in the mRNA populations coding for stage-specif ic proteins. Moreover, the most dramatic changes in chromatin structure observed in eukaryotes, take place durin...

The incidence of type 1 diabetes has been rapidly rising. Environmental factors such as viruses have been implicated as a possible agent accounting for this rise. Enteroviruses have recently been the focus in many research studies as a potential agent in the pathogenesis of type 1 diabetes. The mechanism of viral infection leading to beta cell destruction not only involves multiple pathways but...

An alkyne-azide addition, i.e., click, reaction in conjunction with an electrostatic self-assembly and covalent fixation (ESA-CF) process has been demonstrated to effectively construct a variety of unprecedented multicyclic polymer topologies. A series of single cyclic poly(tetrahydrofuran), poly(THF), precursors having an alkyne group (Ia), an azide group (Ib), two alkyne groups at the opposit...

The alkoxybenzophenanthr id ine alkaloids (coralyne acetosulfate, fagaronine chloride, and nit idine chloride) have been reported to possess ant i leukemic activity in mice. These compounds were tested for inhibi t ion of reverse transcriptase activity of an RNA tumor virus and DNA polymerase, RNA polymerase, and polyadenyl ic acid polymerase activit ies of NIH-Swiss mouse embryos. Reverse tran...

Solid triclosan/cyclodextrin inclusion complexes (TR/CD-IC) were obtained and then incorporated in poly(lactic acid) (PLA) nanofibers via electrospinning. α-CD, β-CD, and γ-CD were tested for the formation of TR/CD-IC by a coprecipitation method; however, the findings indicated that α-CD could not form an inclusion complex with TR, whereas β-CD and γ-CD successfully formed TR/CD-IC crystals, an...