The present research was aimed to develop and characterize a sustained release dry powder inhalable formulation of salbutamol sulphate. The salbutamol sulphate microparticles were prepared by solvent evaporation method using biodegradable polymer poly (D,L-lactic-co-glycolic acid) to produce salbutamol sulphate microparticle mixed with carrier respirable grade lactose for oral inhalation of dry...

Nowadays, there are several efforts in immunotherapy especially biodegradable and biocompatible nano-polymers are using as immunomodulatory to induce cell mediated immune responses [1]. The advantages of nanoparticles have been proved to be potent immunomodulators in several kinds of vaccines to control a release of antigen, higher quality and quantity of immune responses and protect the integr...

This study examines in vitro and in vivo biodegradation and biocompatibility of a thermogelling polymeric material, which we call a mixture hydrogel. The mixture contains two ABA-type triblock copolymers poly(d,l-lactic acid-co-glycolic acid)-b-poly(ethylene glycol)-b-poly(d,l-lactic acid-co-glycolic acid) (PLGA-PEG-PLGA) with different block ratios, and one polymer is soluble in water, but the...

The synthesis of a family of new poly(lactic acid-co-glycerol monostearate) (PLA-PGC18) copolymers and their use as biodegradable polymer dopants is reported to enhance the hydrophobicity of poly(lactic acid-co-glycolic acid) (PLGA) nonwoven meshes. Solutions of PLGA are doped with PLA-PGC18 and electrospun to form meshes with micrometer-sized fibers. Fiber diameter, percent doping, and copolym...

Herein we report the fabrication of engineered poly(lactic acid-co-glycolic acid) nanoparticles via the PRINT (particle replication in nonwetting templates) process with high and efficient loadings of docetaxel, up to 40% (w/w) with encapsulation efficiencies >90%. The PRINT process enables independent control of particle properties leading to a higher degree of tailorability than traditional m...

Submit Manuscript | http://medcraveonline.com Abbreviations: PLGA: Poly Lactic-Co-Glycolic Acid; PEG: Polyethylene Glycol; FDA: Food and Drug Administration; AlgPLGANP: Alginate-PLGA Nanoparticle; PDI: Polydispersity Index; TRF: Tocotrienol Rich Fraction; FA: Folic Acid; α: Alpha; ZP: Zeta Potential; SEM: Scanning Electron Microscopy; PXRD: Powder X ray Diffraction; DSC: Differential Scanning C...