It is important when developing new vaccine systems to give proper attention to the question of delivery. In some cases the judicious choice of a delivery system can provide a greatly enhanced immune response and avoid the need to use a vaccine adjuvant. Delivery systems that have been developed originally for the administration of challenging drug can be used with success for vaccines. Polymer...

Tumor metastases occur through both the cardiovascular and lymphatic circulations. However, the majority of nanoparticle biodistribution studies have been focused on the cardiovascular circulation. In this study, we report the formulation of Cy5-labeled polylactide (Cy5-PLA) nanoparticles with controlled size and surface features and the subsequent evaluation of their lymphatic biodistribution....

Flexible organic phototransistors are fabricated using polylactide (PLA), a polar bio-material, as the dielectric material. The charge trapping effect induced by the polar groups of the PLA layer leads to a photosensitivity close to ≈104. The excellent performance of this new device design is further demonstrated by incorporating the photo-transistors into a sensor array to successfully image a...

The removal of low molecular weight products the reaction and heat withdrawal is one problems bulk polycondensation. Polycondensation under spray conditions an effective way to solve these problems. Based on example reversible lactic acid polycondensation, it was shown that size effects can significantly affect conversion rate, degree polymerization, rate processes. Chemical thermodynamics sugg...

Abstract The article presents the results of comparative studies rheological properties ceramic polymer blend polylactide (PLA) filled with 50 %vol alumina to evaluate possibility obtaining extruded filament for 3D printing.