the seeds of peganum harmala l. ( pgh ) (zygophyllaceae) have been used in moroccan traditional medicine for treatment of a various diseases and to relieve dolorous process. the major objective of this paper was to investigate the analgesic effect of ethyl acetate (eae), butanolic (be) and aqueous (aqe) extracts of seeds of peganum harmala and elucided the possible underlying action mechanism o...

introduction: amnesia or loss of memory is the cardinal hallmark of alzheimer’s disease (ad), a progressive neurodegenerative disorder associated with ageing process. although, ad had been discovered over a century ago, drugs which could cure or halt the progression of the disease are yet to see the light of the day. however, there has been a growing interest in the use of phytomedicines with m...

after central nervous system (cns) injuries, the regeneration process does not work out well except for remyelination process. this remyelination capacity in cns can be mentioned as a worthy example of stem/precursor cell-mediated renewal process. remyelination in cns is mediated by schwann cells which act mainly as remyelinating agents in peripheral nervous system (pns) but several studies hav...

Achillea wilhelmsii have been used in folk remedies. The relaxant effects of the extractof A. wilhelmsii on tracheal chains of guinea pigs were examined. The relaxant effects offour cumulative concentrations of the extract, theophylline and saline were examined bytheir relaxant effects on precontracted tracheal chains of guinea pig by KCl (group 1), 10 μMmethacholine (group 2), incubated tissue...

A daunting mine disaster took place in 13 May 2014 at Soma and 301 men lost their lives. Brief information about the Eynez coal mine and some of the inherent characteristics of the field in terms of their effects on mining are presented. This paper basically concentrates on the factors that played an important role in the occurrence of this disaster. Progress of mine fire, firefighting, and res...

DHIPC (2,4-dichloro-2´-hydroxyl-4´,6´-diisoprenyloxychalcone) is a new chalconecompound. In this study, its antidepressant-like activity of compound DHIPC was evaluated bythe forced swimming test and the tail suspension test in mice. The results showed that DHIPCsignificantly reduced the immobility time for 2 h after treatment through the oral administrationat dose of 10, 20, and 30 mg/kg in th...

Introduction: The effect of esophageal distension (ED) on gastric motility has been well documented, but a few investigations have been carried out on the effect of ED on gastric secretion. The aim of this study was to investigate the effect of ED on gastric acid and pepsin secretion and the mechanism(s) involved. Methods: Male adult Wistar rats (200-240 g) were anesthetized with urethane (1...

Achillea wilhelmsii have been used in folk remedies. The relaxant effects of the extractof A. wilhelmsii on tracheal chains of guinea pigs were examined. The relaxant effects offour cumulative concentrations of the extract, theophylline and saline were examined bytheir relaxant effects on precontracted tracheal chains of guinea pig by KCl (group 1), 10 μMmethacholine (group 2), incubated tissue...