INTRODUCTION The objective of this study was to identify prenatal markers of histological chorioamnionitis (HC) during pPROM using fetal computerized cardiotocography (cCTG). MATERIALS AND METHODS Retrospective review of medical records from pregnant women referred for pPROM between 26 and 34 weeks, in whom placental histology was available, in a tertiary level obstetric service over a 5-year...

OBJECTIVE To study the incidence and outcome of preterm premature rupture of membranes (PPROM). DESIGN Cross-sectional study. SETTING Department of Obstetrics and Gynecology, Faculty of Medicine, Chulalongkorn University. SUBJECTS Ninety five PPROM women who were expectant management and delivered between January 1, 1997 and December 31, 1997. RESULTS The incidence of PPROM was 7.2 per ...

OBJECTIVE Preterm premature rupture of membranes (PPROM) is closely related with maternal and fetal complications. Therefore, early diagnosis is extremely important to provide maternal and fetal well-being. Many inflammatory markers have been evaluated for their ability to diagnose membrane rupture at early stages. We aimed to investigate the relationship between the platelet-to-lymphocyte rati...

BACKGROUND A genetic predisposition to Preterm Labor (PTL) and Preterm Premature Rupture of Membranes (PPROM) has been suggested; however the relevance of polymorphisms and ancestry to susceptibility to PTL and PPROM in different populations remains unclear. The aim of this study was to evaluate the contribution of maternal and fetal SNPs in the IL1B, IL6, IL6R, TNFA, TNFR, IL10, TLR2, TLR4, MM...

The aim of the study was to demonstrate that preterm birth (PTB) is associated with altered C19MC microRNA expression profile in placental tissues. Gene expression of 15 placental specific microRNAs (miR‑512‑5p, miR‑515‑5p, miR‑516‑5p, miR‑517‑5p, miR‑518b, miR‑518f‑5p, miR‑519a, miR‑519d, miR‑519e‑5p, miR‑520a‑5p, miR‑520h, miR‑524‑5p, miR‑525‑5p, miR‑526a and miR‑526b‑5p) was compared between...

Background: Preterm premature rupture of membranes (PPROM) is a major cause preterm birth. There are few reports on vitamin D deficiency associated with PPROM. We aimed to investigate the association between PPROM and levels in maternal plasma umbilical cord blood newborns. Methods: This prospective study included 355 pregnant women who delivered live infants March 2017 December 2018 at medical...

OBJECTIVE To analyze the cervical microbiota in women with preterm prelabor rupture of membranes (PPROM) by pyrosequencing and to document associations between cervical microbiota, cervical inflammatory response, microbial invasion of the amniotic cavity (MIAC), histological chorioamnionitis, and intraamniotic infection (IAI). STUDY DESIGN Sixty-one women with singleton pregnancies complicate...

background preterm premature rupture of membrane (pprom) prior to 37 weeks’ gestation is among the most common obstetrics problems, which is associated with prenatal mortality and several maternal and neonatal complications. history of pprom is a risk factor for recurrence. zinc has an important effect on the strength of membranes by affecting collagen [tensile] strength - a substance with immu...

conclusions vitamin c supplementations after 14th weeks of gestation can prevent from pprom in women with the history of pprom. results pprom occurred in 44.7% of controls and 31.8% of cases (p < 0.05). prom occurred in 34.1% of controls and 18.8% of cases (p < 0.05). pregnancy was terminated at term gestation in 21.2% of controls and 49.4% of cases (p < 0.05). rupture of membranes was signific...