Background: Paraquat (PQ), as the most widely used herbicide in agriculture, induces poisoning in humans and animals mainly through oxidative stress. This study aimed to investigate the protective effects of nano-curcumin compared with curcumin against PQ-induced mitochondrial dysfunction. Materials and Methods: Thirty-six Wistar rats were used in this study. They were separated into 6 groups...

Edaravone, an antioxidant and radical scavenger, showed protective effects against oxidative stress-like condition. Paraquat (PQ) is a toxic herbicide considerable evidence suggests that oxidative stress and mitochondrial dysfunction contribute to PQ toxicity. In this study, protective effect of edaravone against PQ induced toxicity and reactive oxygen species (ROS) generation in A549 cells and...

Paraquat (PQ), is one of the most widely used herbicides all over the world. PQ could induce dopaminergic cell death. Since dopamine involves in memory processing, we investigated the recovery effect of vitamin C on spatial memory along with oxidative stress parameters during PQ induced neurotoxicity in male rats. Rats were divided into five groups (n= 7): control (saline 0.9%), PQ (2.67 and 5 ...

A D(−1)-quadruple is a set of positive integers {a, b, c, d}, with a < b < c < d, such that the product of any two elements from this set is of the form 1+n2 for some integer n. Dujella and Fuchs showed that any such D(−1)-quadruple satisfies a = 1. The D(−1) conjecture states that there is no D(−1)-quadruple. If b = 1+ r2, c = 1+ s2 and d = 1+ t2, then it is known that r, s, t, b, c and d are ...

In this paper we present some problems and their solutions exploiting lattice based root finding techniques. In CaLC 2001, Howgrave-Graham proposed a method to find the Greatest Common Divisor (GCD) of two large integers when one of the integers is exactly known and the other one is known approximately. In this paper, we present three applications of the technique. The first one is to show dete...

Fail-stop signature (FSS) schemes are important primitives because in a fail-stop signature scheme the signer is protected against unlimited powerful adversaries as follows: Even if an adversary breaks the scheme’s underlying computational hard problem and hence forges a signature, then with overwhelming probability the signer is able to prove that a forgery has occurred (i.e. that the underlyi...

Edaravone, an antioxidant and radical scavenger, showed protective effects against oxidative stress-like condition. Paraquat (PQ) is a toxic herbicide considerable evidence suggests that oxidative stress and mitochondrial dysfunction contribute to PQ toxicity. In this study, protective effect of edaravone against PQ induced toxicity and reactive oxygen species (ROS) generation in A549 cells and...

Let D:= (X,B,I) be a 2-design. For each xeX set Bx:= {jeB:xIj}, and define Xh dually for each h e B. We call D reduced if Xh = Xt implies that h = i for all h,ieB. Assume that D is a reduced 2-design with parameters v, b, k, r, X. Let G be a flag transitive automorphism group of D. By F*(G) we mean (as usual) the generalized Fitting subgroup of G which is defined to be the inverse image in G of...

Paraquat (PQ) is a widely used herbicide. However, a large number of cases of accidental or suicidal poisoning from PQ has been reported. Membrane damage induced by lipid peroxidation, inactivation of protein or damage to DNA by radical formation have been suggested as toxicity mechanisms of PQ. In the present work, the effects of atropine, propranolol, procainamide and dipyridamole on PQ-...

A bstract Parity solutions to the strong CP problem are a compelling alternative approaches based on Peccei-Quinn symmetry, particularly given expected violation of global symmetries in theory quantum gravity. The most natural these break parity at low scale, giving rise host experimentally accessible signals. We assess status simplest parity-based solution light LHC data and flavor constraints...