Ensuring quality has become a daily requirement in laboratories. In haemostasis, even more than in other disciplines of biology, quality is determined by a pre-analytical step that encompasses all procedures, starting with the formulation of the medical question, and includes patient preparation, sample collection, handling, transportation, processing, and storage until time of analysis. This s...

ABSTRACT Introduction: Routine urinalysis is among the most requested exams in clinical laboratory, assisting diagnosis of various diseases and treatment follow-up. In this case, pre-analytical phase extremely important because quality sample directly influences analysis interpretation result. Objective: The aim study was to identify main errors routine urine examination a private laboratory th...

Arterial blood gas analyses provide information about the patient's oxygenation, ventilation, and perfusion. Studies have shown that most errors occur during the pre-analytical phase (the processes prior to the actual analysis of the sample). 1st Automatic is an extra module to the existing blood gas analyzer and a partial automation of the pre-analytical phase which is designed to reduce these...

Background and objectives: All three phases of laboratory testing are equally important for improving total quality management, but the pre-analytical phase is the most error-prone. This study aimed to determine the rate and reasons for blood sample rejection in the pre-analytical phase of laboratory testing in a referral hospital in Ruhengeri, Rwanda. Methods: This study was a cross-sectional...

The constantly increasing requests for the measurement of serum 25-hydroxyvitamin D over the last years has led reagent manufacturers to market different automated and semi-automated methods, that being unfortunately not fully harmonized, yield different results. Liquid chromatography coupled to tandem mass spectrometry has more recently been introduced. This approach allows the distinction bet...

Laboratory testing is a highly complex process and, although laboratory services are relatively safe, they are not as safe as they could or should be. Clinical laboratories have long focused their attention on quality control methods and quality assessment programs dealing with analytical aspects of testing. However, a growing body of evidence accumulated in recent decades demonstrates that qua...

The Pre-Project Phase of building construction manages the communication between client organization, user groups and designers. Disconnects and miscommunication in this phase may result in a product that does not fulfill their expectations. Based on literature review, three methods are introduced in order to streamline the communication and improve its precision: a method for criteria manageme...

Variation in pre-analytical procedures can have effects on RNA expression in tissue. Standardization of the pre-analytical workflow is not always an option, therefore it is necessary to know which factors might be of influence and should be noted as meta data in tissuebank databases. Here we describe the discovery and potential use of a RT-qPCR fingerprint of genes sensitive to the ischemic per...

BACKGROUND The present study was designed in quasi-experiment to assess adoption of the essential clauses of particular clinical laboratory quality management requirements based on international organization for standardization (ISO 15189) in hospital laboratories and to evaluate the cost effectiveness of compliance to ISO 15189. METHODS The quality management intervention based on ISO 15189 ...