There have been few studies of the intrathecal position of spinal catheters in continuous spinal anaesthesia. This prospective study was designed to examine radiologically the intrathecal position of 28-gauge spinal catheters. We studied the entry into the subarachnoid space and the intrathecal position of 68 spinal catheters. In 50%, the catheters passed in a cranial direction, in 34% the cath...

Seventy-four patients with proved spontaneous subarachnoid haemorrhage were studied. Sixty-four underwent computed tomography and 55 underwent lumbar puncture. Seven cases deteriorated dramatically after lumbar puncture, six of these showing evidence of cerebral dislocation on further investigation. Four of the seven had not undergone computed tomography and three underwent computed tomography ...

Nusinersen (ISIS-SMNRx or ISIS 396443) is an antisense oligonucleotide drug administered intrathecally to treat spinal muscular atrophy. We summarize lumbar puncture experience in children with spinal muscular atrophy during a phase 1 open-label study of nusinersen and its extension. During the studies, 73 lumbar punctures were performed in 28 patients 2 to 14 years of age with type 2/3 spinal ...

OBJECTIVE To see whether the incidence of cerebral herniation is increased immediately after lumbar puncture in children with bacterial meningitis and whether any children with herniation have normal results on cranial computed tomography. DESIGN Retrospective review of case notes; computed tomograms were read again. SETTING Large paediatric teaching hospital. SUBJECTS 445 children over 3...

PURPOSE To examine the hypothesis that lumbar puncture alone may cause meningeal enhancement in the brain. METHODS We prospectively reviewed the brain MR examinations of all patients from a 6-month period who were studied within 1 month after lumbar puncture. We also retrospectively reviewed all cases of dural-arachnoidal enhancement in the brain from the preceding 18-month period. RESULTS ...

Sir Lumbar puncture (LP) is an essential medical procedure for several clinical conditions. It is an invasive procedure by which physicians can provide sample of cerebrospinal fluid through a needle inserted into the lower lumbar area for diagnostic purposes (meningitis or subarachnoid hemorrhage). Injection of medications into the cerebrospinal fluid "intrathecally", particularly for spinal an...

BACKGROUND Errors in the judgement of puncture level during neuraxial anaesthesia can lead to significant complications. The aim of this study was to assess, in obstetric anaesthesia, the accuracy of clinical determination of the lumbar spinal interspace level, using surface ultrasound imaging as control. METHODS At the anaesthesia follow-up visit, women who had received lumbar neuraxial anae...