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We continue the study of semicompact sets in a topological space. Several properties, mapping properties of semicompact sets are studied. A special interest to SCS spaces is given, where a space X is SCS if every subset of X which is semicompact in X is semiclosed; we study several properties of such spaces, it is mainly shown that a semi-T2 semicompact space is SCS if and only if it is extrema...

Retinoic acid inducible gene-I (RIG-I) is a key intracellular immune receptor for pathogenic RNAs, particularly from RNA viruses. Here, we report the crystal structure of human RIG-I bound to a 5' triphosphorylated RNA hairpin and ADP nucleotide at 2.8 Å resolution. The RNA ligand contains all structural features that are essential for optimal recognition by RIG-I, as it mimics the panhandle-li...

We address the problem of long-term dynamics of tuberculosis (TB) and latent tuberculosis (LTB) in semiclosed communities. These communities are congregate settings with the potential for sustained daily contact for weeks, months, and even years between their members. Basic examples of these communities are prisons, but certain urban/rural communities, some schools, among others could possibly ...