Pathological angiogenesis is the most common cause of blindness at all ages including retinopathy of prematurity, diabetic retinopathy, and age-related macular degeneration. Despite advances in therapy, retinopathy of prematurity remains the most sight-threatening vaso-proliferative retinopathy in children. Herein, we demonstrated that rosmarinic acid has an anti-angiogenic activity to retinal ...

purpose : to evaluate the structural outcomes of treated neonates with retinopathy of prematurity (rop) methods : in this cross-sectional study from april 2008 to august 2009, 859 patients were investigated. these neonates had been consulted at the retinal clinic of farabi eye hospital of tehran university of medical sciences. those with gestational age of no more than 36 weeks and birth weight...

The age at which retinopathy of prematurity was first seen was determined in 143 infants. In all, the initial ophthalmological examination was normal. Birth weights varied from 630 to 2700 g and gestational ages from 24.5 to 40.0 weeks. The median postnatal age at which acute retinopathy of prematurity was first seen was 51 and 40 days for those less than 28 and greater than or equal to 28 week...

to determine the role of blood transfusion protocols on retinopathy of prematurity (rop), a prospective cohort study on 57 premature infants under 1501 grams birth weight was performed. fourteen day-old infants were divided into two groups randomly. infants in group 1 (n=27) received packed red blood cell transfusion only if specific medical signs were met and their hematocrit level was under 3...

Retinopathy of prematurity (ROP) is a disorder characterised by abnormal retinal vascular development, and several risk factors are involved. The condition may be in mild form or it may result in retinal detachment which may eventually cause blindness. The management of the risk factors involved in the disease etiopathogenesis and the treatment by laser photocoagulation performed in early stage...

Arch Ophthalmol. 2005;123(7):991-999. 3. Chiang MF, Jiang L, Gelman R, Du YE, Flynn JT. Interexpert agreement of plus disease diagnosis in retinopathy of prematurity. Arch Ophthalmol. 2007; 125(7):875-880. 4. Gelman R, Martinez-Perez ME, Vanderveen DK, Moskowitz A, Fulton AB. Diagnosis of plus disease in retinopathy of prematurity using Retinal Image multiScale Analysis. Invest Ophthalmol Vis S...

editorial

In this paper, we summarize the development and application of two novel magnetic resonance based measurements of retinal oxygenation in experimental models of retinopathy, including diabetic retinopathy and retinopathy of prematurity. We use 19F-NMR and a small (microl) perfluorocarbon drop positioned in the preretinal vitreous space to make PO2 measurement of the inner retina. In addition, we...