The prognostic value of central systolic blood pressure has been established recently. At present, its noninvasive assessment is limited by the need of dedicated equipment and trained operators. Moreover, ambulatory and home blood pressure monitoring of central pressures are not feasible. An algorithm enabling conventional automated oscillometric blood pressure monitors to assess central systol...

OBJECTIVE Optimal blood pressure control in subjects with diabetes reduces cardiovascular complications. There is theoretical benefit in the assessment of central aortic waveforms including the augmentation index, which is taken as a putative index of stiffness. Transfer functions may be used to reconstruct aortic from radial pressure waveforms; however, a single generalized transfer function m...

BACKGROUND Arterial stiffness of patients with coronary artery disease (CAD), which is expected to be increased due to a generalized atherosclerotic process of human body, may be more evident after the acute increase of blood pressure (BP) or peripheral vascular resistance. Isometric handgrip exercise is a simple and easily applicable method to achieve this goal. We investigated the changes of ...

Spatial properties of noise statistics near unheated, laboratory-scale supersonic jets yield insights into source characteristics and near-field shock formation. Primary findings are (1) waveforms with positive pressure skewness radiate from the source with a directivity upstream of maximum overall level and (2) skewness of the time derivative of the pressure waveforms increases significantly w...

The jet sound quality "crackle" has historically been studied and quantified using the statistics of the pressure waveform. Some investigators have suggested crackle, and its associated shock content, may be better quantified using the statistics of the time derivative of the waveform. Modified waveforms are used to evaluate crackle prediction criteria based on the skewness of each variable. Th...

To clarify the pathophysiological role of dynamic arterial properties in cardiovascular diseases, we attempted to develop a new control system that imposes desired aortic impedance on in situ rat left ventricle. In 38 anesthetized open-chest rats, ascending aortic pressure and flow waveforms were continuously sampled (1,000 Hz). Desired flow waveforms were calculated from measured aortic pressu...

We sought a noninvasive alternative method of monitoring peripheral vascular resistance continuously in humans, based on the analysis of arterial pressure waveforms. Radial arterial pressure waveforms were recorded noninvasively with a tonometer and analysed using a neural network method. To test the accuracy of this method, the peripheral vascular resistance was also determined by an invasive ...

BACKGROUND AND OBJECTIVE According to international standards, autonomic function is assessed by heart rate variability (HRV) calculated from R-R intervals obtained with an electrocardiogram (ECG). However, intra-operative movement artefacts and electrical interference may complicate R-wave detection. Pulse rate variability (PRV) derived from continuous blood pressure measurements may provide a...