We have previously shown that osteosarcomas (OS) have states of increased interstitial fluid pressure (IFP), which correlate with increased proliferation and chemosensitivity. In this study, we hypothesized that constitutively raised IFP in OS regulates angiogenesis. Sixteen patients with the clinical diagnosis of OS underwent blood flow and IFP readings by the wick-in-needle method at the time...

The extraction yield, phenolic content, anthocyanin content and antioxidant activity of extracts from different varieties of red grapes, Cabernet Sauvignon, Merlot, Petit Verdot, Syrah, Tempranillo and Tintilla, using pressurized green solvents have been analyzed. Two techniques were studied and compared: supercritical fluid extraction (SFE) with CO2 + 20% ethanol and pressurized liquid extract...

Introduction: Mechanical stimulation has an effective role in helping to produce more functional engineered articular cartilage tissue for focal defect repair [1]. It is hypothesized that adding direct pressurized fluid flow to the combination of compression and sliding shear acting on chondrocyteseeded hydrogel constructs can significantly increase collagen production. If so, this “hydromechan...

Abrasive flow machining (AFM) is a manufacturing technique that uses the flow of a pressurized abrasive media to remove work piece material. In comparison with other polishing technique, AFM is very efficient, suitable for the finishing of complex inner surfaces. In recent years, hybrid-machining processes have been developed to improve the efficiency of a process by clubbing the advantages of ...

Wetland plants transport oxygen to belowground tissues survive in anoxic sediments, and simultaneously conduct methane (CH4) from the sediment atmosphere. Although plant-mediated is main CH4 emission pathway vegetated wetlands, contribution of areas total emissions wetlands remains uncertain. To accurately quantify these emissions, understanding physiological processes driving crucial. This rev...

Below-grade stormwater storage tunnels are designed to provide relief for collection networks during intense rain events. Air must be evacuated as the tunnel fills and, depending on the system geometry, the air may become pressurized. This research presents an investigation on various ways that the air pressurization influences the water flow. The investigation used an experimental apparatus co...

Use of externally pressurized air bearings allows for the design of mechanical systems requiring extreme precision in positioning. One application is the fine control for the positioning of mirrors in large-scale optical telescopes. Other examples come from applications in robotics and computer hard-drive manufacturing. Pressurized bearings maintain a finite separation between mechanical compon...

We have reported that high-hydrostatic-pressure (HHP) technology is safe and useful for producing various kinds of decellularized tissue. However, the preparation of decellularized or inactivated skin using HHP has not been reported. The objective of this study was thus to prepare inactivated skin from human skin using HHP, and to explore the appropriate conditions of pressurization to inactiva...