The recognition that neonatal death contributes considerably to infant mortality – and hence under five mortality rates – has led many countries to expand services for sick and preterm newborn infants. Indeed, the recent expansion of Special Newborn Care Units in India is having a major impact on the survival of sick and preterm neonates, driving down neonatal and infant mortality rates across ...

Fluid management and dosage regimens of drugs in preterm infants should be based on the glomerular filtration rate. The current methods to determine glomerular filtration rate are invasive, time-consuming, and expensive. In contrast, creatinine clearance can be easy obtained and quickly determined. The purpose of this study was to compare plasma creatinine on the third and seventh day of life i...

Most newborns with complications are identified and cared for in community hospitals or level II perinatal centers (American Academy of Pediatrics [AAP], 2012). Perinatal nurses must have a thorough understanding of pathophysiologic and clinical signs of illness during the immediate newborn period. The length of stay limits the time to identify behavioral cues or subtle changes that could poten...

* Professor titular de Pediatria, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo (USP), Ribeirão Preto, SP. Ao final do século XIX e início do século XX, Stephane Tarnier (1828-1897) e seu aluno Pierre Budin (18461907), ambos obstetras atuando no L ́Hôpital Maternité de Paris, ocupavam-se da sistematização dos cuidados com os recém-nascidos pré-termo1. Em suas lições, cuja le...

During pregnancy, mother's well-being affects directly the newborn development. Some maternal and placental complications, such as gestational diabetes, preeclampsia (PE), preterm delivery and intrauterine growth restriction (IUGR), may contribute to fetal growth deviations or fetal development modifications. Usually the newborn weight correlates positively with placenta weight, showing the int...

Late preterm gestation is an important risk factor for the development of severe neonatal hyperbilirubinemia and kernicterus. An exaggerated hepatic immaturity contributes to the greater prevalence, severity, and duration of neonatal jaundice in late preterm infants. Breast milk feeding is almost uniformly present and large for gestational age status, male sex, and G6PD deficiency are over-repr...

AIM To investigate sodium (NA(+)) potassium (K(+)) adenosine triphosphatase (ATPase) activity in newborn infants at different gestational ages, to elucidate the mechanism underlying poor renal sodium conservation in preterm infants. METHODS Fifty three healthy newborn infants, gestational age 30-42 weeks, were studied. Umbilical cord red blood cell Na(+) K(+)ATPase activity, plasma renin acti...

background & aim:  high-risk pregnancies increase the risk of intensive care unit (icu) and neonatal intensive care unit (nicu) admission in mothers and their newborns. in this study, we aimed to identify the association between the recurrence of high-risk pregnancy and mothers’ previous experience of having an infant admitted to nicu. methods:we performed a cohort, retrospective study to compa...